Artemisinin derivative
This page covers all Artemisinin derivative drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Plasmodium parasites (multiple targets including heme and parasite proteins), Malaria parasite heme; potential cancer cell apoptosis pathways, Plasmodium heme and iron-dependent mechanisms.
Targets
Plasmodium parasites (multiple targets including heme and parasite proteins) · Malaria parasite heme; potential cancer cell apoptosis pathways · Plasmodium heme and iron-dependent mechanisms · Parasite proteins (non-specific alkylation via reactive oxygen species) · Plasmodium heme-dependent activation · Heme iron (parasite-derived); multiple parasite proteins and membranes
Marketed (4)
- artesunate sachets · Pfizer · Infectious Disease
Artesunate is an artemisinin derivative that generates reactive oxygen species and alkylates parasite proteins, killing malaria parasites and other blood-stage pathogens. - Artesunate 2 · University of Oxford · Infectious Disease; Oncology
Artesunate is an artemisinin derivative that generates reactive oxygen species to kill malaria parasites and has immunomodulatory and anti-cancer properties. - artesunate (AS) · London School of Hygiene and Tropical Medicine · Infectious Disease
Artesunate generates reactive oxygen species that damage parasite membranes and proteins, killing malaria parasites. - Artesunate (Comparator) · Pfizer · Infectious Disease
Artesunate is an artemisinin derivative that generates reactive oxygen species and alkylates parasite proteins, killing malaria parasites and other pathogens.
Phase 3 pipeline (2)
- AS (Guilin Pharmaceuticals) · London School of Hygiene and Tropical Medicine · Infectious Disease
AS is an artemisinin-based antimalarial compound that generates reactive oxygen species to kill malaria parasites. - Artemether Sublingual Spray · Proto Pharma Ltd · Infectious Disease
Artemether is an artemisinin derivative that kills malaria parasites by generating reactive oxygen species that damage parasite proteins and membranes.