Amide local anesthetic

This page covers all Amide local anesthetic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Nerve sodium channels, Sodium channel alpha subunits; brain (Types I, II, III), Sodium channel protein type 5 subunit alpha.

Targets

Nerve sodium channels · Sodium channel alpha subunits; brain (Types I, II, III) · Sodium channel protein type 5 subunit alpha · Sodium channel protein type 1 subunit alpha · Cytochrome P450 2D6

Marketed (8)

• Bupivacaine Hydrochloride And Epinephrine · Pfizer
  Bupivacaine blocks nerve impulse generation and conduction by increasing electrical excitation threshold and slowing action potential rise.
• Bupivacaine Hydrochloride And Epinephrine · Pfizer
  Bupivacaine blocks nerve impulse generation and conduction by increasing electrical excitation threshold and slowing action potential rise.
• Septocaine · Neuroscience
  Articaine HCl blocks nerve impulses by increasing the threshold for electrical excitation, slowing nerve impulse propagation, and reducing the rate of rise of the action potential.
• Naropin · Fresenius Kabi · Pain
• Bupivacaine Hydrochloride And Epinephrine · Pfizer
  Bupivacaine blocks nerve impulse generation and conduction by increasing electrical excitation threshold and slowing action potential rise.
• Carbocaine · Eastman Kodak · Pain
• Bupivacaine Hydrochloride And Epinephrine · Innocoll · Ophthalmology
  Bupivacaine works by blocking nerve impulses to prevent pain signals from reaching the brain.
• Bupivacaine Hydrochloride And Epinephrine · Pfizer
  Bupivacaine Hydrochloride blocks nerve impulses by inhibiting sodium channels.