What are ACTH analog drugs?

ACTH analog drugs are pharmacologic agents that share a common mechanism (typically targeting Melanocortin-2 receptor (MC2R)). 4 are currently marketed, with 1 more in clinical development.

What are the marketed ACTH analog drugs?

Marketed ACTH analog drugs include Acthar low dose (40 U), Tricortin 1000, Acthar high dose (80 U), ACTHAR Gel (ACTH).

ACTH analog

4 marketed 1 in Phase 3

This page covers all ACTH analog drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Melanocortin-2 receptor (MC2R).

Targets

Melanocortin-2 receptor (MC2R)

Marketed (4)

Acthar low dose (40 U) · NYU Langone Health · Immunology
Acthar is a synthetic adrenocorticotropic hormone (ACTH) that stimulates the adrenal cortex to produce and release cortisol and other corticosteroids.
Tricortin 1000 · Fidia Farmaceutici s.p.a. · Endocrinology
Tricortin 1000 is a corticotropin (ACTH) analog that stimulates the adrenal cortex to produce endogenous corticosteroids.
Acthar high dose (80 U) · NYU Langone Health · Immunology / Rheumatology / Neurology
Acthar is a synthetic adrenocorticotropic hormone (ACTH) that stimulates the adrenal cortex to produce and release cortisol and other corticosteroids.
ACTHAR Gel (ACTH) · University of Colorado, Denver · Immunology
ACTHAR Gel is a synthetic adrenocorticotropic hormone (ACTH) that stimulates the adrenal cortex to produce and release cortisol and other corticosteroids.

Phase 3 pipeline (1)

Acthar Injectable Product · Attune Health Research, Inc. · Immunology / Rheumatology
Acthar is a synthetic adrenocorticotropic hormone (ACTH) that stimulates the adrenal cortex to produce and release cortisol and other corticosteroids.