Who are Zanaflex®'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lucemyra, Neurontin, Iopidine, Dipivefrin, Sudafed, Catapres-Tts-1.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Zanaflex® — Competitive Intelligence Brief

Zanaflex® (Zanaflex®) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alpha-2 adrenergic agonist. Area: Neurology.

marketed Alpha-2 adrenergic agonist Alpha-2A adrenergic receptor Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Zanaflex® (Zanaflex®) — Icahn School of Medicine at Mount Sinai. Zanaflex is an alpha-2 adrenergic agonist that reduces muscle spasticity by increasing inhibitory neurotransmission in the spinal cord.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Zanaflex® TARGET	Zanaflex®	Icahn School of Medicine at Mount Sinai	marketed	Alpha-2 adrenergic agonist	Alpha-2A adrenergic receptor
Lucemyra	LOFEXIDINE	Biocorrx Pharms	marketed	lofexidine	Alpha-2A adrenergic receptor	2018-01-01
Neurontin	gabapentin	Generic (originally Parke-Davis/Pfizer)	marketed	Gabapentinoid (anticonvulsant/neuropathic pain agent)	Large neutral amino acids transporter small subunit 1, Adenosine receptor A1, Alpha-2A adrenergic receptor	1993-12-30
Iopidine	APRACLONIDINE	Harrow Health	marketed	alpha-Adrenergic Agonist	Alpha-2A adrenergic receptor	1987-01-01
Dipivefrin	dipivefrine	AbbVie	marketed	Adrenergic Receptor Agonist	Alpha-2A adrenergic receptor	1980-01-01
Sudafed	pseudoephedrine	Generic (multiple manufacturers)	marketed	Nasal decongestant (sympathomimetic)	Alpha-1A adrenergic receptor, Alpha-2A adrenergic receptor, Beta-2 adrenergic receptor	1976-01-01
Catapres-Tts-1	CLONIDINE	Lavipharm	marketed	Central alpha-2 Adrenergic Agonist	Alpha-2A adrenergic receptor	1974-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2027-04-17 — Catapres-Tts-1 · 8337890 · Formulation · US
2031-09-08 — Catapres-Tts-1 · 8623409 · Formulation · US

Sponsor landscape (Alpha-2 adrenergic agonist class)

USWM, LLC (dba US WorldMeds) · 2 drugs in this class
China International Neuroscience Institution · 1 drug in this class
Icahn School of Medicine at Mount Sinai · 1 drug in this class
Eye Therapies, LLC · 1 drug in this class
Galderma R&D · 1 drug in this class
Guangzhou Women and Children's Medical Center · 1 drug in this class
Derm Research, PLLC · 1 drug in this class
Irmandade da Santa Casa de Misericordia de Sao Paulo · 1 drug in this class
KK Women's and Children's Hospital · 1 drug in this class
American University of Beirut Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Zanaflex® — Competitive Intelligence Brief. https://druglandscape.com/ci/zanaflex. Accessed 2026-05-13.

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