Who are Yohimbin's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Abilify, Risperdal, Risperdal, Delysid, Ergot, Abilify.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Yohimbin — Competitive Intelligence Brief

Yohimbin (YOHIMBINE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: yohimbine. Area: Cardiovascular.

discontinued yohimbine 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Yohimbin (YOHIMBINE). Yohimbine works by blocking the alpha-2A adrenergic receptor, which increases the release of norepinephrine and epinephrine, leading to increased alertness and energy.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Yohimbin TARGET	YOHIMBINE		discontinued	yohimbine	5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6
Abilify	aripiprazole	Generic (originally Otsuka/BMS)	marketed	Third-generation antipsychotic (D2 partial agonist)	5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6	2002-11-15
Risperdal	risperidone	Johnson & Johnson (Janssen)	marketed	Atypical Antipsychotic [EPC]	5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6	1993-12-29
Risperdal	Risperdal	Ohio State University	marketed		5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6
Delysid	LYSERGIDE		marketed	lysergide	5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6
Ergot	Ergot	Samuel Lunenfeld Research Institute, Mount Sinai Hospital	marketed		5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6
Abilify	Abilify	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	marketed		5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-06-26 — Risperdal · 10406160 · Formulation · US
2026-07-28 — Abilify · 9125939 · Method of Use · US
2026-09-14 — Abilify · 7978064 · Formulation · US
2026-09-26 — Risperdal · 9597402 · Formulation · US
2026-09-26 — Risperdal · 10058554 · Method of Use · US
2026-11-05 — Risperdal · 11110093 · Formulation · US
2027-03-02 — Abilify · 8759350 · Method of Use · US
2027-11-12 — Risperdal · 8741327 · Formulation · US
2027-11-12 — Risperdal · 8221778 · Formulation · US
2027-11-19 — Abilify · 9444503 · Formulation · US
2028-02-13 — Risperdal · 11712475 · Method of Use · US
2028-02-13 — Risperdal · 10010612 · Formulation · US
2028-02-13 — Risperdal · 9180197 · Formulation · US
2028-02-13 — Risperdal · 11013809 · Formulation · US
2028-02-13 — Risperdal · 10376590 · Method of Use · US
2028-02-13 — Risperdal · 9186413 · Method of Use · US
2028-12-16 — Abilify · 9119554 · Formulation · US
2029-03-05 — Abilify · 9258035 · Formulation · US
2029-03-05 — Abilify · 9060708 · Formulation · US
2029-04-09 — Abilify · 8674825 · Formulation · US
2029-07-06 — Abilify · 8956288 · Formulation · US
2029-07-26 — Abilify · 10441194 · Formulation · US
2029-08-19 — Abilify · 8945005 · Formulation · US
2029-09-15 — Abilify · 9433371 · Formulation · US
2029-12-05 — Abilify · 8718193 · Formulation · US
2029-12-15 — Abilify · 9149577 · Formulation · US
2030-03-29 — Abilify · 8847766 · Formulation · US
2030-04-27 — Abilify · 8545402 · Formulation · US
2030-06-21 — Abilify · 8114021 · Formulation · US
2030-09-15 — Abilify · 11464423 · Formulation · US

Sponsor landscape (yohimbine class)

· 1 drug in this class

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Cite this brief

Drug Landscape (2026). Yohimbin — Competitive Intelligence Brief. https://druglandscape.com/ci/yohimbine. Accessed 2026-05-14.

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