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Vorinostat (VOR) — Competitive Intelligence Brief
marketed
Histone deacetylase (HDAC) inhibitor
Histone deacetylases (HDAC1, HDAC2, HDAC3, HDAC6, HDAC8)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Vorinostat (VOR) (Vorinostat (VOR)) — University of North Carolina, Chapel Hill. Vorinostat inhibits histone deacetylases (HDACs), leading to accumulation of acetylated histones and altered gene expression that promotes cancer cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Vorinostat (VOR) TARGET | Vorinostat (VOR) | University of North Carolina, Chapel Hill | marketed | Histone deacetylase (HDAC) inhibitor | Histone deacetylases (HDAC1, HDAC2, HDAC3, HDAC6, HDAC8) | |
| Low dose valproate | Low dose valproate | Mario Negri Institute for Pharmacological Research | marketed | Histone deacetylase (HDAC) inhibitor | Histone deacetylases (HDACs) | |
| AL8326 tablets | AL8326 tablets | Advenchen Laboratories Nanjing Ltd. | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) | |
| HIP2101 | HIP2101 | Hanmi Pharmaceutical Company Limited | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) | |
| Ifupinostat Hydrochloride for Injection | Ifupinostat Hydrochloride for Injection | BeBetter Med Inc | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) | |
| Belinostat Injection | Belinostat Injection | Acrotech Biopharma Inc. | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) | |
| SPARC0912 | SPARC0912 | Sun Pharma Advanced Research Company Limited | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Histone deacetylase (HDAC) inhibitor class)
- Acrotech Biopharma Inc. · 1 drug in this class
- Advenchen Laboratories Nanjing Ltd. · 1 drug in this class
- BeBetter Med Inc · 1 drug in this class
- Hanmi Pharmaceutical Company Limited · 1 drug in this class
- Mario Negri Institute for Pharmacological Research · 1 drug in this class
- Sun Pharma Advanced Research Company Limited · 1 drug in this class
- University of North Carolina, Chapel Hill · 1 drug in this class
- medac GmbH · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Vorinostat (VOR) — Competitive Intelligence Brief. https://druglandscape.com/ci/vorinostat-vor. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing