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Vonoprazan-Amoxicillin Dual Therapy — Competitive Intelligence Brief
marketed
Potassium-competitive acid blocker (PCAB) + beta-lactam antibiotic combination
H+/K+-ATPase (vonoprazan); bacterial cell wall peptidoglycan (amoxicillin)
Gastroenterology / Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Vonoprazan-Amoxicillin Dual Therapy (Vonoprazan-Amoxicillin Dual Therapy) — Nanjing First Hospital, Nanjing Medical University. Vonoprazan inhibits gastric acid secretion while amoxicillin kills Helicobacter pylori bacteria, together eradicating H. pylori infection.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Vonoprazan-Amoxicillin Dual Therapy TARGET | Vonoprazan-Amoxicillin Dual Therapy | Nanjing First Hospital, Nanjing Medical University | marketed | Potassium-competitive acid blocker (PCAB) + beta-lactam antibiotic combination | H+/K+-ATPase (vonoprazan); bacterial cell wall peptidoglycan (amoxicillin) | |
| Vonoprazan + amoxicillin | Vonoprazan + amoxicillin | The Third Xiangya Hospital of Central South University | marketed | Potassium-competitive acid blocker (PCAB) + beta-lactam antibiotic combination | H+/K+-ATPase (vonoprazan); bacterial cell wall peptidoglycan (amoxicillin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Potassium-competitive acid blocker (PCAB) + beta-lactam antibiotic combination class)
- Nanjing First Hospital, Nanjing Medical University · 1 drug in this class
- The Third Xiangya Hospital of Central South University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Vonoprazan-Amoxicillin Dual Therapy — Competitive Intelligence Brief. https://druglandscape.com/ci/vonoprazan-amoxicillin-dual-therapy. Accessed 2026-05-17.
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