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Vonoprazan, Amoxicillin and Clarithromycin — Competitive Intelligence Brief
marketed
Potassium-competitive acid blocker (PCAB) + beta-lactam antibiotic + macrolide antibiotic combination
H+/K+-ATPase (vonoprazan); bacterial cell wall and protein synthesis (amoxicillin and clarithromycin)
Gastroenterology / Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Vonoprazan, Amoxicillin and Clarithromycin (Vonoprazan, Amoxicillin and Clarithromycin) — Kaohsiung Medical University. This triple-therapy combination eradicates Helicobacter pylori by suppressing gastric acid (vonoprazan) while simultaneously killing the bacteria with two antibiotics (amoxicillin and clarithromycin).
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Vonoprazan, Amoxicillin and Clarithromycin TARGET | Vonoprazan, Amoxicillin and Clarithromycin | Kaohsiung Medical University | marketed | Potassium-competitive acid blocker (PCAB) + beta-lactam antibiotic + macrolide antibiotic combination | H+/K+-ATPase (vonoprazan); bacterial cell wall and protein synthesis (amoxicillin and clarithromycin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Potassium-competitive acid blocker (PCAB) + beta-lactam antibiotic + macrolide antibiotic combination class)
- Kaohsiung Medical University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Vonoprazan, Amoxicillin and Clarithromycin — Competitive Intelligence Brief. https://druglandscape.com/ci/vonoprazan-amoxicillin-and-clarithromycin. Accessed 2026-05-16.
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