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Verquvo — Competitive Intelligence Brief
marketed
Soluble Guanylate Cyclase Stimulator [EPC]
Guanylate cyclase soluble subunit beta-1
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Verquvo (VERICIGUAT) — Merck & Co.. Verquvo works by stimulating the enzyme guanylate cyclase to increase levels of a molecule called cGMP, which helps to relax blood vessels and improve heart function.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Verquvo TARGET | VERICIGUAT | Merck & Co. | marketed | Soluble Guanylate Cyclase Stimulator [EPC] | Guanylate cyclase soluble subunit beta-1 | 2021-01-01 |
| Adempas | RIOCIGUAT | Bayer | marketed | Soluble Guanylate Cyclase Stimulator [EPC] | Guanylate cyclase soluble subunit beta-1 | 2013-01-01 |
| Adempas | Adempas | University of Colorado, Denver | marketed | Guanylate cyclase soluble subunit beta-1, cAMP-specific 3',5'-cyclic phosphodiesterase 7B | ||
| Riociguat (Adempas) | Riociguat (Adempas) | Chinese University of Hong Kong | marketed | Soluble guanylate cyclase stimulator | Soluble guanylate cyclase (sGC) | |
| Riociguat Oral Product | Riociguat Oral Product | University of Calgary | marketed | Soluble guanylate cyclase stimulator | Soluble guanylate cyclase (sGC) | |
| Riociguat Pill | Riociguat Pill | University of Arizona | phase 3 | Soluble guanylate cyclase stimulator | Soluble guanylate cyclase (sGC) | |
| SOC: Soluble guanylate cyclase stimulator | SOC: Soluble guanylate cyclase stimulator | Actelion | phase 3 | Soluble guanylate cyclase stimulator | Soluble guanylate cyclase (sGC) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Soluble Guanylate Cyclase Stimulator [EPC] class)
- Bayer · 1 drug in this class
- Merck & Co. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Verquvo — Competitive Intelligence Brief. https://druglandscape.com/ci/vericiguat. Accessed 2026-05-13.
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