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Venlafaxine XR + Mirtazapine — Competitive Intelligence Brief
marketed
Antidepressant combination (SNRI + NaSSA)
Serotonin transporter, norepinephrine transporter, alpha-2 adrenergic receptors, 5-HT2 receptors, 5-HT3 receptors
Psychiatry / Mental Health
Small molecule
Live · refreshed every 30 min
Target snapshot
Venlafaxine XR + Mirtazapine (Venlafaxine XR + Mirtazapine) — National Institute of Mental Health (NIMH). This combination increases serotonin and norepinephrine levels in the brain while also enhancing serotonergic signaling through alpha-2 antagonism, used to treat depression.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Venlafaxine XR + Mirtazapine TARGET | Venlafaxine XR + Mirtazapine | National Institute of Mental Health (NIMH) | marketed | Antidepressant combination (SNRI + NaSSA) | Serotonin transporter, norepinephrine transporter, alpha-2 adrenergic receptors, 5-HT2 receptors, 5-HT3 receptors |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antidepressant combination (SNRI + NaSSA) class)
- National Institute of Mental Health (NIMH) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Venlafaxine XR + Mirtazapine — Competitive Intelligence Brief. https://druglandscape.com/ci/venlafaxine-xr-mirtazapine. Accessed 2026-05-18.
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