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Zelboraf — Competitive Intelligence Brief

Zelboraf (vemurafenib) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Kinase Inhibitor [EPC]. Area: Oncology.

marketed Kinase Inhibitor [EPC] Serine/threonine-protein kinase B-raf Oncology Live · refreshed every 30 min

Target snapshot

Zelboraf (vemurafenib) — Hoffmann La Roche. Zelboraf blocks the activity of the B-raf protein, which is involved in cell growth and division.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Zelboraf TARGET vemurafenib Hoffmann La Roche marketed Kinase Inhibitor [EPC] Serine/threonine-protein kinase B-raf 2011-01-01
Tafinlar dabrafenib Novartis marketed Kinase Inhibitor Serine/threonine-protein kinase B-raf 2013-01-01
Itovebi INAVOLISIB Genentech Inc marketed Kinase Inhibitor [EPC] 2025-01-01
Romvimza VIMSELTINIB Deciphera Pharms marketed Kinase Inhibitor [EPC] 2025-01-01
Hernexeos ZONGERTINIB Boehringer Ingelheim marketed Kinase Inhibitor [EPC] 2025-01-01
Wayrilz RILZABRUTINIB Genzyme Corp marketed Kinase Inhibitor [EPC] 2025-01-01
Itovebi inavolisib Pfizer marketed Kinase Inhibitor [EPC] phosphatidylinositol 3-kinase (PI3K) alpha (PIK3CA) 2024-01-01

Recent regulatory actions (last 90 days)

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Kinase Inhibitor [EPC] class)

  1. · 12 drugs in this class
  2. Pfizer · 7 drugs in this class
  3. Novartis · 3 drugs in this class
  4. Bayer · 2 drugs in this class
  5. Boehringer Ingelheim · 2 drugs in this class
  6. AstraZeneca · 2 drugs in this class
  7. Beigene Usa Inc · 1 drug in this class
  8. BeiGene · 1 drug in this class
  9. AbbVie · 1 drug in this class
  10. Bristol · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Zelboraf — Competitive Intelligence Brief. https://druglandscape.com/ci/vemurafenib. Accessed 2026-05-13.

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