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Vehicle to AGN-199201 — Competitive Intelligence Brief

Vehicle to AGN-199201 (Vehicle to AGN-199201) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Neurokinin-1 (NK1) receptor antagonist. Area: Pain Management / Neurology.

phase 3 Neurokinin-1 (NK1) receptor antagonist NK1 receptor Pain Management / Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Vehicle to AGN-199201 (Vehicle to AGN-199201) — Allergan. AGN-199201 is a selective antagonist of the neurokinin-1 (NK1) receptor that modulates pain signaling in the central nervous system.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Vehicle to AGN-199201 TARGET Vehicle to AGN-199201 Allergan phase 3 Neurokinin-1 (NK1) receptor antagonist NK1 receptor
Aprepitant plus Ondansetron Aprepitant plus Ondansetron University of Pittsburgh marketed NK1 receptor antagonist + 5-HT3 receptor antagonist combination NK1 receptor (aprepitant); 5-HT3 receptor (ondansetron)
Akynzeo solution Akynzeo solution Helsinn Healthcare SA marketed NK1 receptor antagonist / 5-HT3 receptor antagonist combination NK1 receptor (netupitant component); 5-HT3 receptor (palonosetron component)
Ramosetron, Aprepitant, Dexamethasone Ramosetron, Aprepitant, Dexamethasone Hallym University Medical Center marketed 5-HT3 antagonist / NK1 antagonist / corticosteroid combination 5-HT3 receptor, NK1 receptor, glucocorticoid receptor
EMEND EMEND Merck Sharp & Dohme LLC marketed Neurokinin-1 (NK1) receptor antagonist NK1 receptor (neurokinin-1 receptor)
Fosaprepitant for Injection Fosaprepitant for Injection Montefiore Medical Center marketed NK1 receptor antagonist NK1 receptor (neurokinin-1 receptor)
Dexamethasone, Ondansetron, Aprepitant Dexamethasone, Ondansetron, Aprepitant Ottawa Hospital Research Institute marketed Antiemetic combination (corticosteroid + 5-HT3 antagonist + NK1 antagonist) Glucocorticoid receptor, 5-HT3 receptor, NK1 receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Neurokinin-1 (NK1) receptor antagonist class)

  1. Merck Sharp & Dohme LLC · 4 drugs in this class
  2. Organon and Co · 2 drugs in this class
  3. Allergan · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Vehicle to AGN-199201 — Competitive Intelligence Brief. https://druglandscape.com/ci/vehicle-to-agn-199201. Accessed 2026-05-17.

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