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Vehicle to AGN-199201 — Competitive Intelligence Brief
phase 3
Neurokinin-1 (NK1) receptor antagonist
NK1 receptor
Pain Management / Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Vehicle to AGN-199201 (Vehicle to AGN-199201) — Allergan. AGN-199201 is a selective antagonist of the neurokinin-1 (NK1) receptor that modulates pain signaling in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Vehicle to AGN-199201 TARGET | Vehicle to AGN-199201 | Allergan | phase 3 | Neurokinin-1 (NK1) receptor antagonist | NK1 receptor | |
| Aprepitant plus Ondansetron | Aprepitant plus Ondansetron | University of Pittsburgh | marketed | NK1 receptor antagonist + 5-HT3 receptor antagonist combination | NK1 receptor (aprepitant); 5-HT3 receptor (ondansetron) | |
| Akynzeo solution | Akynzeo solution | Helsinn Healthcare SA | marketed | NK1 receptor antagonist / 5-HT3 receptor antagonist combination | NK1 receptor (netupitant component); 5-HT3 receptor (palonosetron component) | |
| Ramosetron, Aprepitant, Dexamethasone | Ramosetron, Aprepitant, Dexamethasone | Hallym University Medical Center | marketed | 5-HT3 antagonist / NK1 antagonist / corticosteroid combination | 5-HT3 receptor, NK1 receptor, glucocorticoid receptor | |
| EMEND | EMEND | Merck Sharp & Dohme LLC | marketed | Neurokinin-1 (NK1) receptor antagonist | NK1 receptor (neurokinin-1 receptor) | |
| Fosaprepitant for Injection | Fosaprepitant for Injection | Montefiore Medical Center | marketed | NK1 receptor antagonist | NK1 receptor (neurokinin-1 receptor) | |
| Dexamethasone, Ondansetron, Aprepitant | Dexamethasone, Ondansetron, Aprepitant | Ottawa Hospital Research Institute | marketed | Antiemetic combination (corticosteroid + 5-HT3 antagonist + NK1 antagonist) | Glucocorticoid receptor, 5-HT3 receptor, NK1 receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Neurokinin-1 (NK1) receptor antagonist class)
- Merck Sharp & Dohme LLC · 4 drugs in this class
- Organon and Co · 2 drugs in this class
- Allergan · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Vehicle to AGN-199201 — Competitive Intelligence Brief. https://druglandscape.com/ci/vehicle-to-agn-199201. Accessed 2026-05-17.
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