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Entyvio — Competitive Intelligence Brief
marketed
Integrin Receptor Antagonist [EPC]
Integrin alpha-4/beta-7
Gastroenterology
Live · refreshed every 30 min
Target snapshot
Entyvio (vedolizumab) — Takeda. Vedolizumab is a humanized monoclonal antibody that binds α4β7 integrin and blocks its interaction with MAdCAM-1, preventing memory T-lymphocyte migration into inflamed gastrointestinal tissue.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Entyvio TARGET | vedolizumab | Takeda | marketed | Integrin Receptor Antagonist [EPC] | Integrin alpha-4/beta-7 | |
| Tysabri | Tysabri | University of Chicago | marketed | Integrin alpha-4/beta-1, Integrin alpha-4/beta-7 | ||
| Tysabri | NATALIZUMAB | Biogen Idec | marketed | Integrin Receptor Antagonist [EPC] | α4β1 and α4β7 integrins | 2004-01-01 |
| TYRUKO | NATALIZUMAB-SZTN | SANDOZ INC | marketed | Integrin Receptor Antagonist [EPC] |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Integrin Receptor Antagonist [EPC] class)
- Biogen Idec · 1 drug in this class
- SANDOZ INC · 1 drug in this class
- Takeda · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Entyvio — Competitive Intelligence Brief. https://druglandscape.com/ci/vedolizumab. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing