Who are VB-111 + Paclitaxel's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Inlyta, REGORAFENIB, PONATINIB HYDROCHLORIDE, PAZOPANIB HYDROCHLORIDE, PAZOPANIB, Sutent.

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Last reviewed 2026-06-09 · How we verify

VB-111 + Paclitaxel — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

VB-111 + Paclitaxel (VB-111 + Paclitaxel) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: VEGF aptamer and microtubule inhibitor. Area: Oncology.

phase 3 VEGF aptamer and microtubule inhibitor VEGF Oncology Small molecule Live · refreshed every 30 min

Target snapshot

VB-111 + Paclitaxel (VB-111 + Paclitaxel) — Vascular Biogenics Ltd. operating as VBL Therapeutics. VB-111 is a targeted anti-vascular endothelial growth factor (VEGF) aptamer that inhibits tumor growth by blocking VEGF, while Paclitaxel is a microtubule inhibitor that disrupts cell division.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
VB-111 + Paclitaxel TARGET	VB-111 + Paclitaxel	Vascular Biogenics Ltd. operating as VBL Therapeutics	phase 3	VEGF aptamer and microtubule inhibitor	VEGF
Inlyta	Axitinib	Pfizer	marketed	Receptor tyrosine kinase inhibitor	Vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2, VEGFR-3	2012-01-01
REGORAFENIB	REGORAFENIB		marketed		RET, VEGFR1, VEGFR2, VEGFR3, KIT, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR2, TIE2, DDR2, TrkA, Eph2A, RAF-1, BRAF, BRAF V600E, SAPK2, PTK5, Abl, CSF1R	2012-01-01
PONATINIB HYDROCHLORIDE	PONATINIB HYDROCHLORIDE		marketed		ABL, T315I mutant ABL, VEGFR, PDGFR, FGFR, EPH receptors, SRC family, KIT, RET, TIE2, FLT3	2012-01-01
PAZOPANIB HYDROCHLORIDE	PAZOPANIB HYDROCHLORIDE		marketed		VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-α, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms	2009-01-01
PAZOPANIB	PAZOPANIB		marketed	Kinase Inhibitor [EPC]	VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-ɑ, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms	2009-01-01
Sutent	Sunitinib Malate	Pfizer	marketed	Small molecule kinase inhibitor	Receptor tyrosine kinases (RTKs): PDGFRα, PDGFRβ, VEGFR1, VEGFR2, VEGFR3, KIT, FLT3, CSF-1R, RET	2006-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (VEGF aptamer and microtubule inhibitor class)

Vascular Biogenics Ltd. operating as VBL Therapeutics · 1 drug in this class

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Cite this brief

Drug Landscape (2026). VB-111 + Paclitaxel — Competitive Intelligence Brief. https://druglandscape.com/ci/vb-111-paclitaxel. Accessed 2026-06-09.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing