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Vaginal TFV Gel — Competitive Intelligence Brief
marketed
Nucleotide reverse transcriptase inhibitor (microbicide)
HIV reverse transcriptase
Infectious Disease / HIV Prevention
Small molecule
Live · refreshed every 30 min
Target snapshot
Vaginal TFV Gel (Vaginal TFV Gel) — University of Washington. Tenofovir (TFV) gel applied vaginally blocks HIV reverse transcriptase to prevent sexual transmission of HIV.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Vaginal TFV Gel TARGET | Vaginal TFV Gel | University of Washington | marketed | Nucleotide reverse transcriptase inhibitor (microbicide) | HIV reverse transcriptase | |
| Regimen:TDF+3TC+EFV | Regimen:TDF+3TC+EFV | National Center for AIDS/STD Control and Prevention, China CDC | marketed | Antiretroviral combination therapy (NRTI + NNRTI) | HIV reverse transcriptase | |
| DTG/3TC/ABC + ELV/COBI/FTC/TAF | DTG/3TC/ABC + ELV/COBI/FTC/TAF | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination therapy (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) | HIV integrase, HIV reverse transcriptase | |
| didanosine + lamivudine + efavirenz | didanosine + lamivudine + efavirenz | Clinical Trial Agency of HIV Study Group | marketed | Antiretroviral combination therapy (NRTI + NNRTI) | HIV reverse transcriptase | |
| Didanosine (enteric-coated) | Didanosine (enteric-coated) | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase | |
| Lamivudine / Abacavir Sulfate | Lamivudine / Abacavir Sulfate | GlaxoSmithKline | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase | |
| AZT+3TC+ABV (Trizivir) | AZT+3TC+ABV (Trizivir) | Fundacion SEIMC-GESIDA | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nucleotide reverse transcriptase inhibitor (microbicide) class)
- University of Washington · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Vaginal TFV Gel — Competitive Intelligence Brief. https://druglandscape.com/ci/vaginal-tfv-gel. Accessed 2026-05-16.
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