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Vaginal TFV Gel — Competitive Intelligence Brief

Vaginal TFV Gel (Vaginal TFV Gel) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Nucleotide reverse transcriptase inhibitor (microbicide). Area: Infectious Disease / HIV Prevention.

marketed Nucleotide reverse transcriptase inhibitor (microbicide) HIV reverse transcriptase Infectious Disease / HIV Prevention Small molecule Live · refreshed every 30 min

Target snapshot

Vaginal TFV Gel (Vaginal TFV Gel) — University of Washington. Tenofovir (TFV) gel applied vaginally blocks HIV reverse transcriptase to prevent sexual transmission of HIV.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Vaginal TFV Gel TARGET Vaginal TFV Gel University of Washington marketed Nucleotide reverse transcriptase inhibitor (microbicide) HIV reverse transcriptase
Regimen:TDF+3TC+EFV Regimen:TDF+3TC+EFV National Center for AIDS/STD Control and Prevention, China CDC marketed Antiretroviral combination therapy (NRTI + NNRTI) HIV reverse transcriptase
DTG/3TC/ABC + ELV/COBI/FTC/TAF DTG/3TC/ABC + ELV/COBI/FTC/TAF Fundacion SEIMC-GESIDA marketed Antiretroviral combination therapy (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) HIV integrase, HIV reverse transcriptase
didanosine + lamivudine + efavirenz didanosine + lamivudine + efavirenz Clinical Trial Agency of HIV Study Group marketed Antiretroviral combination therapy (NRTI + NNRTI) HIV reverse transcriptase
Didanosine (enteric-coated) Didanosine (enteric-coated) Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections marketed Nucleoside reverse transcriptase inhibitor (NRTI) HIV reverse transcriptase
Lamivudine / Abacavir Sulfate Lamivudine / Abacavir Sulfate GlaxoSmithKline marketed Nucleoside reverse transcriptase inhibitor (NRTI) combination HIV reverse transcriptase
AZT+3TC+ABV (Trizivir) AZT+3TC+ABV (Trizivir) Fundacion SEIMC-GESIDA marketed Nucleoside reverse transcriptase inhibitor (NRTI) combination HIV reverse transcriptase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Nucleotide reverse transcriptase inhibitor (microbicide) class)

  1. University of Washington · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Vaginal TFV Gel — Competitive Intelligence Brief. https://druglandscape.com/ci/vaginal-tfv-gel. Accessed 2026-05-16.

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