Who are USL255's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Medium-dose anrikefon, Flecainide controlled release, Propafenone i.v., TAK-816, Group VTI, TV-46000.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

USL255 — Competitive Intelligence Brief

USL255 (USL255) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: sodium-activated potassium channel inhibitor. Area: Cardiovascular.

phase 3 sodium-activated potassium channel inhibitor Nav1.5 Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

USL255 (USL255) — Upsher-Smith Laboratories. USL255 is a small molecule that acts as a selective inhibitor of the sodium-activated potassium channel, Nav1.5.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
USL255 TARGET	USL255	Upsher-Smith Laboratories	phase 3	sodium-activated potassium channel inhibitor	Nav1.5
Medium-dose anrikefon	Medium-dose anrikefon	Peking University First Hospital	marketed	Sodium channel blocker	Nav1.5
Flecainide controlled release	Flecainide controlled release	MEDA Pharma GmbH & Co. KG	marketed	Class IC antiarrhythmic agent	Cardiac voltage-gated sodium channel (Nav1.5)
Propafenone i.v.	Propafenone i.v.	Charles University, Czech Republic	marketed	Class IC antiarrhythmic agent	Cardiac sodium channel (Nav1.5)
TAK-816	TAK-816	Takeda	phase 3	Sodium-activated potassium channel inhibitor	Nav1.5
Group VTI	Group VTI	Kasr El Aini Hospital	phase 3	sodium-activated potassium channel inhibitor	Nav1.5
TV-46000	TV-46000	Teva Branded Pharmaceutical Products R&D, Inc.	phase 3	Sodium-activated potassium channel inhibitor	Nav1.5

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (sodium-activated potassium channel inhibitor class)

Aurobac Therapeutics SAS · 1 drug in this class
Kasr El Aini Hospital · 1 drug in this class
Maimonides Medical Center · 1 drug in this class
Pfizer · 1 drug in this class
Teva Branded Pharmaceutical Products R&D, Inc. · 1 drug in this class
Upsher-Smith Laboratories · 1 drug in this class

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Cite this brief

Drug Landscape (2026). USL255 — Competitive Intelligence Brief. https://druglandscape.com/ci/usl255. Accessed 2026-05-13.

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