Who are Ulipristal acetate (UPA)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Natazia, Faslodex, Ortho Evra, Elocon, Gynorest, Progesterone.

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Last reviewed 2026-05-16 · How we verify

Ulipristal acetate (UPA) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ulipristal acetate (UPA) (Ulipristal acetate (UPA)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Selective progesterone receptor modulator. Area: Women's health.

phase 3 Selective progesterone receptor modulator Progesterone receptor Women's health Small molecule Live · refreshed every 30 min

Target snapshot

Ulipristal acetate (UPA) (Ulipristal acetate (UPA)) — Allergan. Ulipristal acetate acts as a selective progesterone receptor modulator (SPRM) to prevent ovulation and thicken cervical mucus, thereby inhibiting sperm penetration.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Ulipristal acetate (UPA) TARGET	Ulipristal acetate (UPA)	Allergan	phase 3	Selective progesterone receptor modulator	Progesterone receptor
Natazia	DIENOGEST	Mochida Pharmaceutical Co., Ltd.	marketed	Progestin	Progesterone receptor	2010-01-01
Faslodex	fulvestrant	AstraZeneca	marketed	Estrogen Receptor Antagonist [EPC]	Progesterone receptor	2002-01-01
Ortho Evra	NORELGESTROMIN		marketed	Estrogen [EPC]	Progesterone receptor	2001-01-01
Elocon	MOMETASONE FUROATE	Merck & Co.	marketed	Corticosteroid	Progesterone receptor	1987-01-01
Gynorest	DYDROGESTERONE	Solvay	marketed	dydrogesterone	Progesterone receptor	1982-01-01
Progesterone	Progesterone plus HCG	Dunamenti REK Istenhegyi IVF Center	marketed	Progesterone [EPC]	progesterone receptor, luteinizing hormone/choriogonadotropin receptor	1978-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-11-29 — Elocon · 7544192 · Method of Use · US
2027-06-12 — Elocon · 8025635 · Formulation · US
2028-01-30 — Natazia · 8153616 · US
2031-10-03 — Elocon · 10357640 · Method of Use · US
2032-02-08 — Elocon · 8763222 · Formulation · US
2034-02-14 — Faslodex · 10188663 · Formulation · US
2034-02-14 — Faslodex · 9833459 · Formulation · US
2034-03-13 — Elocon · 10406332 · Formulation · US
2034-05-17 — Faslodex · 9271990 · Formulation · US
2034-11-24 — Elocon · 10232152 · Formulation · US

Sponsor landscape (Selective progesterone receptor modulator class)

Allergan · 1 drug in this class
PregLem SA · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ulipristal acetate (UPA) — Competitive Intelligence Brief. https://druglandscape.com/ci/ulipristal-acetate-upa. Accessed 2026-05-16.

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