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UFT (uracil, tegafur) — Competitive Intelligence Brief
phase 3
Fluoropyrimidine antimetabolite
Thymidylate synthase
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
UFT (uracil, tegafur) (UFT (uracil, tegafur)) — Taiho Pharmaceutical Co., Ltd.. UFT is a combination of uracil and tegafur that inhibits thymidylate synthase to block DNA synthesis and induce cancer cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| UFT (uracil, tegafur) TARGET | UFT (uracil, tegafur) | Taiho Pharmaceutical Co., Ltd. | phase 3 | Fluoropyrimidine antimetabolite | Thymidylate synthase | |
| Xeloda | capecitabine | Cheplapharm | marketed | Nucleoside Metabolic Inhibitor [EPC] | Thymidylate synthase | 1998-01-01 |
| Fudr | FLOXURIDINE | marketed | Antimetabolite [EPC] | Thymidylate synthase | 1970-01-01 | |
| Folic Acid | FOLIC ACID | Pfizer | marketed | Vitamin C [EPC] | Thymidylate synthase | 1946-01-01 |
| Phthalin | PHENOLPHTHALEIN | marketed | phenolphthalein | Thymidylate synthase, Thymidylate synthase | ||
| XELODA [capecitabine] | XELODA [capecitabine] | Hoffmann-La Roche | marketed | Fluoropyrimidine antimetabolite | Thymidylate synthase | |
| Capecitabine (Xeloda®) | Capecitabine (Xeloda®) | National Cancer Center, Korea | marketed | Fluoropyrimidine antimetabolite | Thymidylate synthase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Fluoropyrimidine antimetabolite class)
- Federation Francophone de Cancerologie Digestive · 2 drugs in this class
- National Cancer Center, Korea · 2 drugs in this class
- Hoffmann-La Roche · 1 drug in this class
- Japan Clinical Oncology Group · 1 drug in this class
- Jiangxi Provincial Cancer Hospital · 1 drug in this class
- Peter MacCallum Cancer Centre, Australia · 1 drug in this class
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · 1 drug in this class
- Taiho Pharmaceutical Co., Ltd. · 1 drug in this class
- The First Affiliated Hospital of Henan University of Science and Technology · 1 drug in this class
- UNICANCER · 1 drug in this class
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Cite this brief
Drug Landscape (2026). UFT (uracil, tegafur) — Competitive Intelligence Brief. https://druglandscape.com/ci/uft-uracil-tegafur. Accessed 2026-05-16.
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