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UFT adjuvant chemotherapy — Competitive Intelligence Brief

UFT adjuvant chemotherapy (UFT adjuvant chemotherapy) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimetabolite chemotherapy. Area: Oncology.

phase 3 Antimetabolite chemotherapy Thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

UFT adjuvant chemotherapy (UFT adjuvant chemotherapy) — Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan. UFT is a combination of uracil and tegafur (a prodrug of fluorouracil) that inhibits thymidylate synthase to disrupt DNA synthesis in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
UFT adjuvant chemotherapy TARGET UFT adjuvant chemotherapy Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan phase 3 Antimetabolite chemotherapy Thymidylate synthase
Xeloda capecitabine Cheplapharm marketed Nucleoside Metabolic Inhibitor [EPC] Thymidylate synthase 1998-01-01
Fudr FLOXURIDINE marketed Antimetabolite [EPC] Thymidylate synthase 1970-01-01
Folic Acid FOLIC ACID Pfizer marketed Vitamin C [EPC] Thymidylate synthase 1946-01-01
Erlotinib, Pemetrexed Erlotinib, Pemetrexed Hunan Province Tumor Hospital marketed EGFR tyrosine kinase inhibitor + antifolate antimetabolite EGFR; thymidylate synthase and folate-dependent enzymes
Phthalin PHENOLPHTHALEIN marketed phenolphthalein Thymidylate synthase, Thymidylate synthase
Irinotecan, 5FU, leucovorin Irinotecan, 5FU, leucovorin Asan Medical Center marketed Chemotherapy combination (topoisomerase I inhibitor + antimetabolite) Topoisomerase I; thymidylate synthase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimetabolite chemotherapy class)

  1. Hoffmann-La Roche · 1 drug in this class
  2. Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
  3. Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan · 1 drug in this class

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Cite this brief

Drug Landscape (2026). UFT adjuvant chemotherapy — Competitive Intelligence Brief. https://druglandscape.com/ci/uft-adjuvant-chemotherapy. Accessed 2026-05-16.

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