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Tunlametinib plus Vemurafenib — Competitive Intelligence Brief
phase 3
BRAF inhibitor + MEK inhibitor combination
BRAF V600E and MEK1/2
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Tunlametinib plus Vemurafenib (Tunlametinib plus Vemurafenib) — Shanghai Kechow Pharma, Inc.. This combination blocks BRAF and MEK signaling in the MAPK pathway to inhibit growth of BRAF-mutant melanoma and other cancers.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Tunlametinib plus Vemurafenib TARGET | Tunlametinib plus Vemurafenib | Shanghai Kechow Pharma, Inc. | phase 3 | BRAF inhibitor + MEK inhibitor combination | BRAF V600E and MEK1/2 | |
| Encorafenib and Binimetinib | Encorafenib and Binimetinib | Pierre Fabre Medicament | phase 3 | BRAF inhibitor + MEK inhibitor combination | BRAF V600E/K and MEK1/2 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (BRAF inhibitor + MEK inhibitor combination class)
- Pierre Fabre Medicament · 1 drug in this class
- Shanghai Kechow Pharma, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Tunlametinib plus Vemurafenib — Competitive Intelligence Brief. https://druglandscape.com/ci/tunlametinib-plus-vemurafenib. Accessed 2026-05-15.
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