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Trifarotene 0.005 % Topical Cream — Competitive Intelligence Brief
phase 3
retinoid
RAR-gamma
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Trifarotene 0.005 % Topical Cream (Trifarotene 0.005 % Topical Cream) — Teva Pharmaceuticals USA. Trifarotene is a retinoic acid receptor gamma (RAR-gamma) agonist that modulates the expression of genes involved in cell differentiation and proliferation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Trifarotene 0.005 % Topical Cream TARGET | Trifarotene 0.005 % Topical Cream | Teva Pharmaceuticals USA | phase 3 | retinoid | RAR-gamma | |
| tretinoin 0.025% cream | tretinoin 0.025% cream | Wake Forest University | marketed | Retinoid | Retinoic acid receptors (RAR-alpha, RAR-beta, RAR-gamma) | |
| Tretinoin gel | Tretinoin gel | Bausch Health Americas, Inc. | marketed | Retinoid | Retinoic acid receptors (RAR-alpha, RAR-beta, RAR-gamma) | |
| Tretinoin cream 0.05 | Tretinoin cream 0.05 | Massachusetts General Hospital | marketed | Retinoid | Retinoic acid receptors (RAR-alpha, RAR-beta, RAR-gamma) | |
| Tazorac Cream, 0.1% | Tazorac Cream, 0.1% | Dr. Reddy's Laboratories Limited | phase 3 | Retinoid | Retinoic acid receptor (RAR), particularly RAR-beta and RAR-gamma | |
| Sohonos | PALOVAROTENE | Ipsen | marketed | Retinoid [EPC] | Retinoic acid receptor gamma | 2023-01-01 |
| TRIFAROTENE | TRIFAROTENE | marketed | Retinoid [EPC] | 2019-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (retinoid class)
- Galderma R&D · 2 drugs in this class
- Encube Ethicals Pvt. Ltd. · 1 drug in this class
- Fougera Pharmaceuticals Inc. · 1 drug in this class
- Kowa Company, Ltd. · 1 drug in this class
- South Plains Oncology Consortium · 1 drug in this class
- Stiefel, a GSK Company · 1 drug in this class
- Actavis Inc. · 1 drug in this class
- Teva Pharmaceuticals USA · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Trifarotene 0.005 % Topical Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/trifarotene-0-005-topical-cream. Accessed 2026-05-18.
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