Who are tremelimumab (treme)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Imjudo, Nivolumab in combination with Ipilimumab, Fotemustine and Ipilimumab, Tremelimumab (Regimen 1), APVO101, Adjuvant Nivolumab and Ipilimumab.

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Last reviewed 2026-05-16 · How we verify

tremelimumab (treme) — Competitive Intelligence Brief

tremelimumab (treme) (tremelimumab (treme)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CTLA-4 inhibitor. Area: Oncology.

marketed CTLA-4 inhibitor CTLA-4 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

tremelimumab (treme) (tremelimumab (treme)) — AstraZeneca. Tremelimumab is a monoclonal antibody that blocks CTLA-4 on T cells, removing an inhibitory signal and enhancing anti-tumor immune responses.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
tremelimumab (treme) TARGET	tremelimumab (treme)	AstraZeneca	marketed	CTLA-4 inhibitor	CTLA-4
Imjudo	TREMELIMUMAB	AstraZeneca	marketed	CTLA-4-directed Blocking Antibody [EPC]	CTLA-4	2022-01-01
Nivolumab in combination with Ipilimumab	Nivolumab in combination with Ipilimumab	Bristol-Myers Squibb	marketed	Checkpoint inhibitor combination (PD-1 inhibitor + CTLA-4 inhibitor)	PD-1 and CTLA-4
Fotemustine and Ipilimumab	Fotemustine and Ipilimumab	Italian Network for Tumor Biotherapy Foundation	phase 3	Chemotherapy + immune checkpoint inhibitor combination	DNA alkylation (fotemustine); CTLA-4 (ipilimumab)
Tremelimumab (Regimen 1)	Tremelimumab (Regimen 1)	AstraZeneca	phase 3	CTLA-4 inhibitor	CTLA-4
APVO101	APVO101	Medexus Pharma, Inc.	phase 3	Dual checkpoint inhibitor	PD-1 and CTLA-4
Adjuvant Nivolumab and Ipilimumab	Adjuvant Nivolumab and Ipilimumab	Universitätsklinikum Hamburg-Eppendorf	phase 3	PD-1 inhibitor and CTLA-4 inhibitor combination	PD-1 and CTLA-4

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CTLA-4 inhibitor class)

AstraZeneca · 3 drugs in this class
Federation Francophone de Cancerologie Digestive · 1 drug in this class
Providence Health & Services · 1 drug in this class
Shanghai Henlius Biotech · 1 drug in this class
TSH Biopharm Corporation Limited · 1 drug in this class
Takara Bio Inc. · 1 drug in this class
The Netherlands Cancer Institute · 1 drug in this class

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Cite this brief

Drug Landscape (2026). tremelimumab (treme) — Competitive Intelligence Brief. https://druglandscape.com/ci/tremelimumab-treme. Accessed 2026-05-16.

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