Who are tremelimumab (anti-CTLA4)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Imjudo, tremelimumab (treme), Nivolumab in combination with Ipilimumab, Tremelimumab (Regimen 2), APVO101, AK102.

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Last reviewed 2026-05-17 · How we verify

tremelimumab (anti-CTLA4) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

tremelimumab (anti-CTLA4) (tremelimumab (anti-CTLA4)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Anti-CTLA4 monoclonal antibody. Area: Oncology.

phase 3 Anti-CTLA4 monoclonal antibody CTLA-4 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

tremelimumab (anti-CTLA4) (tremelimumab (anti-CTLA4)) — AstraZeneca. Tremelimumab is an anti-CTLA4 monoclonal antibody that blocks the CTLA-4 receptor, enhancing T-cell activation and proliferation.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
tremelimumab (anti-CTLA4) TARGET	tremelimumab (anti-CTLA4)	AstraZeneca	phase 3	Anti-CTLA4 monoclonal antibody	CTLA-4
Imjudo	TREMELIMUMAB	AstraZeneca	marketed	CTLA-4-directed Blocking Antibody [EPC]	CTLA-4	2022-01-01
tremelimumab (treme)	tremelimumab (treme)	AstraZeneca	marketed	CTLA-4 inhibitor	CTLA-4
Nivolumab in combination with Ipilimumab	Nivolumab in combination with Ipilimumab	Bristol-Myers Squibb	marketed	Checkpoint inhibitor combination (PD-1 inhibitor + CTLA-4 inhibitor)	PD-1 and CTLA-4
Tremelimumab (Regimen 2)	Tremelimumab (Regimen 2)	AstraZeneca	phase 3	CTLA-4 inhibitor	CTLA-4
APVO101	APVO101	Medexus Pharma, Inc.	phase 3	Dual checkpoint inhibitor	PD-1 and CTLA-4
AK102	AK102	Akeso	phase 3	Bispecific checkpoint inhibitor	PD-1 and CTLA-4

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Anti-CTLA4 monoclonal antibody class)

AstraZeneca · 1 drug in this class

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Cite this brief

Drug Landscape (2026). tremelimumab (anti-CTLA4) — Competitive Intelligence Brief. https://druglandscape.com/ci/tremelimumab-anti-ctla4. Accessed 2026-05-17.

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