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Imjudo — Competitive Intelligence Brief
marketed
CTLA-4-directed Blocking Antibody [EPC]
CTLA-4
Oncology
Monoclonal antibody
Live · refreshed every 30 min
Target snapshot
Imjudo (TREMELIMUMAB) — AstraZeneca. Tremelimumab-actl binds to CTLA-4, blocking its interaction with CD80 and CD86, thereby enhancing T-cell activation and reducing tumor growth.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Imjudo TARGET | TREMELIMUMAB | AstraZeneca | marketed | CTLA-4-directed Blocking Antibody [EPC] | CTLA-4 | 2022-01-01 |
| tremelimumab (treme) | tremelimumab (treme) | AstraZeneca | marketed | CTLA-4 inhibitor | CTLA-4 | |
| Nivolumab in combination with Ipilimumab | Nivolumab in combination with Ipilimumab | Bristol-Myers Squibb | marketed | Checkpoint inhibitor combination (PD-1 inhibitor + CTLA-4 inhibitor) | PD-1 and CTLA-4 | |
| Neoadjuvant ipilimumab + nivolumab | Neoadjuvant ipilimumab + nivolumab | The Netherlands Cancer Institute | phase 3 | Immune checkpoint inhibitor combination | PD-1 and CTLA-4 | |
| tremelimumab (anti-CTLA4) | tremelimumab (anti-CTLA4) | AstraZeneca | phase 3 | Anti-CTLA4 monoclonal antibody | CTLA-4 | |
| APVO101 | APVO101 | Medexus Pharma, Inc. | phase 3 | Dual checkpoint inhibitor | PD-1 and CTLA-4 | |
| AK102 | AK102 | Akeso | phase 3 | Bispecific checkpoint inhibitor | PD-1 and CTLA-4 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (CTLA-4-directed Blocking Antibody [EPC] class)
- · 1 drug in this class
- ASTRAZENECA AB · 1 drug in this class
- AstraZeneca · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Imjudo — Competitive Intelligence Brief. https://druglandscape.com/ci/tremelimumab. Accessed 2026-05-14.
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