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Treatment with PCSK9 inhibitors — Competitive Intelligence Brief
phase 3
PCSK9 inhibitor
PCSK9
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Treatment with PCSK9 inhibitors (Treatment with PCSK9 inhibitors) — Beijing Anzhen Hospital. PCSK9 inhibitors block the PCSK9 protein, which normally degrades LDL receptors, thereby increasing LDL receptor availability on liver cells to remove more LDL cholesterol from the blood.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Treatment with PCSK9 inhibitors TARGET | Treatment with PCSK9 inhibitors | Beijing Anzhen Hospital | phase 3 | PCSK9 inhibitor | PCSK9 | |
| Repatha | EVOLOCUMAB | Repatha | marketed | PCSK9 Inhibitor [EPC] | PCSK9 | 2015-01-01 |
| Evolocumab Prefilled Syringe | Evolocumab Prefilled Syringe | University of Erlangen-Nürnberg Medical School | marketed | PCSK9 inhibitor (monoclonal antibody) | PCSK9 | |
| Praluent (Alirocumab) | Praluent (Alirocumab) | Federico II University | marketed | PCSK9 inhibitor (monoclonal antibody) | PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) | |
| Repatha® | Repatha® | Sejong General Hospital | marketed | PCSK9 inhibitor (monoclonal antibody) | PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) | |
| Evolocumab combined with statins | Evolocumab combined with statins | Zibo Central Hospital | marketed | PCSK9 inhibitor (monoclonal antibody) | PCSK9 | |
| LEQVIO | LEQVIO | University of Louisville | marketed | PCSK9 inhibitor (siRNA) | PCSK9 mRNA |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (PCSK9 inhibitor class)
- Amgen · 4 drugs in this class
- Bayer · 2 drugs in this class
- Allergan · 2 drugs in this class
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. · 1 drug in this class
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III · 1 drug in this class
- Hospital General Universitario Gregorio Marañon · 1 drug in this class
- Novartis · 1 drug in this class
- Shire · 1 drug in this class
- Vincentage Pharma Co., Ltd · 1 drug in this class
- Wolfson Medical Center · 1 drug in this class
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- Treatment with PCSK9 inhibitors CI watch — RSS
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- Treatment with PCSK9 inhibitors CI watch — JSON
- Treatment with PCSK9 inhibitors alone — RSS
- Whole PCSK9 inhibitor class — RSS
Cite this brief
Drug Landscape (2026). Treatment with PCSK9 inhibitors — Competitive Intelligence Brief. https://druglandscape.com/ci/treatment-with-pcsk9-inhibitors. Accessed 2026-05-17.
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