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treatment of TKI in CML — Competitive Intelligence Brief
phase 3
Tyrosine kinase inhibitor
BCR-ABL
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
treatment of TKI in CML (treatment of TKI in CML) — Poitiers University Hospital. This drug targets the BCR-ABL protein to inhibit cancer cell growth in chronic myeloid leukemia.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| treatment of TKI in CML TARGET | treatment of TKI in CML | Poitiers University Hospital | phase 3 | Tyrosine kinase inhibitor | BCR-ABL | |
| Nilotinib 300 mg. | Nilotinib 300 mg. | King Abdullah International Medical Research Center | marketed | BCR-ABL tyrosine kinase inhibitor | BCR-ABL | |
| Dasatinib Tablets | Dasatinib Tablets | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | marketed | BCR-ABL tyrosine kinase inhibitor | BCR-ABL, SRC family kinases | |
| imatinib (IM) | imatinib (IM) | First Affiliated Hospital, Sun Yat-Sen University | marketed | Tyrosine kinase inhibitor | BCR-ABL, KIT, PDGFRA | |
| DW6012(Dasidiem tab. 10/100mg) | DW6012(Dasidiem tab. 10/100mg) | Dong Wha Pharmaceutical Co. Ltd. | marketed | Tyrosine kinase inhibitor combination | BCR-ABL, SRC family kinases | |
| Imatinib mesylate (STI571) | Imatinib mesylate (STI571) | M.D. Anderson Cancer Center | phase 3 | Tyrosine kinase inhibitor | BCR-ABL, PDGF receptor, c-KIT | |
| Nilotinib, Imatinib | Nilotinib, Imatinib | Seoul St. Mary's Hospital | phase 3 | Tyrosine kinase inhibitor (TKI) | BCR-ABL, KIT, PDGFRA |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Tyrosine kinase inhibitor class)
- Jiangsu HengRui Medicine Co., Ltd. · 5 drugs in this class
- Centre Leon Berard · 2 drugs in this class
- AB Science · 2 drugs in this class
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- Betta Pharmaceuticals Co., Ltd. · 1 drug in this class
- Angion Biomedica Corp · 1 drug in this class
- Beijing InnoCare Pharma Tech Co., Ltd. · 1 drug in this class
- Chang-Ming Huang, Prof. · 1 drug in this class
- Deciphera Pharmaceuticals, LLC · 1 drug in this class
- AstraZeneca · 1 drug in this class
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Cite this brief
Drug Landscape (2026). treatment of TKI in CML — Competitive Intelligence Brief. https://druglandscape.com/ci/treatment-of-tki-in-cml. Accessed 2026-05-17.
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