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Trazodone + PAP therapy — Competitive Intelligence Brief
marketed
Serotonin antagonist and reuptake inhibitor (SARI) + mechanical ventilation device
Serotonin transporter (SERT); serotonin 5-HT2A receptor antagonism
Psychiatry / Sleep Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
Trazodone + PAP therapy (Trazodone + PAP therapy) — VA Office of Research and Development. Trazodone is a serotonin antagonist and reuptake inhibitor (SARI) that increases serotonin availability, combined with positive airway pressure (PAP) therapy to mechanically maintain open airways during sleep.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Trazodone + PAP therapy TARGET | Trazodone + PAP therapy | VA Office of Research and Development | marketed | Serotonin antagonist and reuptake inhibitor (SARI) + mechanical ventilation device | Serotonin transporter (SERT); serotonin 5-HT2A receptor antagonism |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Serotonin antagonist and reuptake inhibitor (SARI) + mechanical ventilation device class)
- VA Office of Research and Development · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Trazodone + PAP therapy — Competitive Intelligence Brief. https://druglandscape.com/ci/trazodone-pap-therapy. Accessed 2026-05-16.
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