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Desyrel — Competitive Intelligence Brief
marketed
SARI (Serotonin antagonist and reuptake inhibitor)
HLA class I histocompatibility antigen, A-3 alpha chain, D(4) dopamine receptor, 5-hydroxytryptamine receptor 1A
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Desyrel (trazodone) — Generic (originally Angelini/Pragmaten). Serotonin antagonist and reuptake inhibitor (SARI) that blocks 5-HT2A receptors and H1 receptors, used primarily as a sedative-hypnotic at low doses.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Desyrel TARGET | trazodone | Generic (originally Angelini/Pragmaten) | marketed | SARI (Serotonin antagonist and reuptake inhibitor) | HLA class I histocompatibility antigen, A-3 alpha chain, D(4) dopamine receptor, 5-hydroxytryptamine receptor 1A | 1981-12-24 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (SARI (Serotonin antagonist and reuptake inhibitor) class)
- Generic (originally Angelini/Pragmaten) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Desyrel — Competitive Intelligence Brief. https://druglandscape.com/ci/trazodone. Accessed 2026-05-15.
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