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Trastuzumab + Pertuzumab — Competitive Intelligence Brief
marketed
HER2-targeted monoclonal antibody combination
HER2 (human epidermal growth factor receptor 2)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Trastuzumab + Pertuzumab (Trastuzumab + Pertuzumab) — Massachusetts General Hospital. Trastuzumab and pertuzumab are monoclonal antibodies that block HER2 signaling by binding to different epitopes on the HER2 receptor, preventing tumor cell growth in HER2-positive cancers.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Trastuzumab + Pertuzumab TARGET | Trastuzumab + Pertuzumab | Massachusetts General Hospital | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Pertuzumab + trastuzumab | Pertuzumab + trastuzumab | European Organisation for Research and Treatment of Cancer - EORTC | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Pertuzumab and Trastuzumab | Pertuzumab and Trastuzumab | QuantumLeap Healthcare Collaborative | marketed | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| FDC of Pertuzumab and Trastuzumab SC | FDC of Pertuzumab and Trastuzumab SC | Hoffmann-La Roche | phase 3 | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Pertuzumab and Trastuzumab FDC SC | Pertuzumab and Trastuzumab FDC SC | Hoffmann-La Roche | phase 3 | HER2-targeted monoclonal antibody combination | HER2 (human epidermal growth factor receptor 2) | |
| Docetaxel combined + Trastuzumab +Pertuzumab | Docetaxel combined + Trastuzumab +Pertuzumab | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | phase 3 | Chemotherapy + HER2-targeted monoclonal antibody combination | HER2 (trastuzumab and pertuzumab); microtubule stabilization (docetaxel) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (HER2-targeted monoclonal antibody combination class)
- Hoffmann-La Roche · 2 drugs in this class
- European Organisation for Research and Treatment of Cancer - EORTC · 1 drug in this class
- Massachusetts General Hospital · 1 drug in this class
- QuantumLeap Healthcare Collaborative · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Trastuzumab + Pertuzumab — Competitive Intelligence Brief. https://druglandscape.com/ci/trastuzumab-pertuzumab. Accessed 2026-05-16.
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