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Trastuzumab and neratinib — Competitive Intelligence Brief
phase 3
HER2-targeted combination therapy (monoclonal antibody + tyrosine kinase inhibitor)
HER2 (human epidermal growth factor receptor 2)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Trastuzumab and neratinib (Trastuzumab and neratinib) — Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University. Trastuzumab and neratinib together block HER2 signaling through complementary mechanisms: trastuzumab is a monoclonal antibody that binds HER2 extracellularly, while neratinib is a tyrosine kinase inhibitor that irreversibly blocks HER2 and other ErbB family kinases intracellularly.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Trastuzumab and neratinib TARGET | Trastuzumab and neratinib | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | phase 3 | HER2-targeted combination therapy (monoclonal antibody + tyrosine kinase inhibitor) | HER2 (human epidermal growth factor receptor 2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (HER2-targeted combination therapy (monoclonal antibody + tyrosine kinase inhibitor) class)
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Trastuzumab and neratinib — Competitive Intelligence Brief. https://druglandscape.com/ci/trastuzumab-and-neratinib. Accessed 2026-05-17.
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