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tranexamic acid (Exacyl®) — Competitive Intelligence Brief
phase 3
Antifibrinolytic
Lysine receptor on plasminogen
Oncology, Surgery
Small molecule
Live · refreshed every 30 min
Target snapshot
tranexamic acid (Exacyl®) (tranexamic acid (Exacyl®)) — Institut Kassab d'Orthopédie. Tranexamic acid works by inhibiting the activation of plasminogen to plasmin, thereby preventing the breakdown of fibrin clots.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| tranexamic acid (Exacyl®) TARGET | tranexamic acid (Exacyl®) | Institut Kassab d'Orthopédie | phase 3 | Antifibrinolytic | Lysine receptor on plasminogen | |
| Trasylol | APROTININ | Bayer | marketed | Antifibrinolytic Agent | Plasminogen | 1993-01-01 |
| Cyklokapron | TRANEXAMIC ACID | Exela Pharma | marketed | Antifibrinolytic Agent [EPC] | Plasminogen | 1986-01-01 |
| Amicar | AMINOCAPROIC ACID | Epic Pharma Llc | marketed | Antifibrinolytic Agent [EPC] | Plasminogen | 1964-01-01 |
| Tranexamic Acid Irrigation | Tranexamic Acid Irrigation | University of Wisconsin, Madison | marketed | Antifibrinolytic agent | Plasminogen / Plasmin | |
| Tranexamic Acid Dosage 1 | Tranexamic Acid Dosage 1 | Chinese Academy of Medical Sciences, Fuwai Hospital | marketed | Antifibrinolytic agent | Plasminogen / Plasmin | |
| aPCC, aPCC + TXA | aPCC, aPCC + TXA | Oslo University Hospital | marketed | Prothrombin complex concentrate with antifibrinolytic agent | Vitamin K-dependent clotting factors (II, VII, IX, X); plasminogen |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antifibrinolytic class)
- Ain Shams University · 1 drug in this class
- Bayer · 1 drug in this class
- German Heart Center · 1 drug in this class
- Institut Kassab d'Orthopédie · 1 drug in this class
- Miller Orthopedic Specialists · 1 drug in this class
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Cite this brief
Drug Landscape (2026). tranexamic acid (Exacyl®) — Competitive Intelligence Brief. https://druglandscape.com/ci/tranexamic-acid-exacyl. Accessed 2026-06-09.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing