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Yondelis — Competitive Intelligence Brief

Yondelis (TRABECTEDIN) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alkylating Drug [EPC]. Area: Oncology.

marketed Alkylating Drug [EPC] Proto-oncogene tyrosine-protein kinase Src Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Yondelis (TRABECTEDIN) — Janssen Prods. Yondelis works by binding to DNA and causing interstrand crosslinks, thereby inhibiting cancer cell growth.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Yondelis TARGET TRABECTEDIN Janssen Prods marketed Alkylating Drug [EPC] Proto-oncogene tyrosine-protein kinase Src 2015-01-01
Adenovite ADENOSINE PHOSPHATE marketed Adenosine Receptor Agonist Proto-oncogene tyrosine-protein kinase Src
Yondelis Yondelis Johnson & Johnson Pharmaceutical Research & Development, L.L.C. marketed Proto-oncogene tyrosine-protein kinase Src, Nuclear receptor subfamily 1 group I member 2
Pepaxto MELPHALAN FLUFENAMIDE Oncopeptides Ab marketed Alkylating Drug 2021-01-01
Zepzelca LURBINECTEDIN Jazz Pharmaceuticals marketed Alkylating Drug [EPC] 2020-01-01
Treanda BENDAMUSTINE Baxter marketed Alkylating Drug Histone deacetylase 6 2008-01-01
Temodar temozolomide Merck & Co. marketed Alkylating Drug [EPC] 1999-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Alkylating Drug [EPC] class)

  1. · 3 drugs in this class
  2. Waylis · 2 drugs in this class
  3. Baxter · 1 drug in this class
  4. Bayer · 1 drug in this class
  5. Janssen Prods · 1 drug in this class
  6. Jazz Pharmaceuticals · 1 drug in this class
  7. Kyowa Kirin Co., Ltd. · 1 drug in this class
  8. Merck & Co. · 1 drug in this class
  9. Recordati · 1 drug in this class
  10. Teva · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Yondelis — Competitive Intelligence Brief. https://druglandscape.com/ci/trabectedin. Accessed 2026-05-13.

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