Who are TPO-RAs's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Promacta, Nplate, rhTPO combined with Herombopag + CsA, CsA+ATG+Herombopag, Avatrombopag Oral Tablet, CsA+Herombopag.

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Last reviewed 2026-05-14 · How we verify

TPO-RAs — Competitive Intelligence Brief

TPO-RAs (TPO-RAs) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Thrombopoietin receptor agonist. Area: Hematology.

marketed Thrombopoietin receptor agonist TPO receptor (MPLS) Hematology Small molecule Live · refreshed every 30 min

Target snapshot

TPO-RAs (TPO-RAs) — Institute of Hematology & Blood Diseases Hospital, China. TPO-RAs (thrombopoietin receptor agonists) stimulate the thrombopoietin receptor to increase platelet production in the bone marrow.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
TPO-RAs TARGET	TPO-RAs	Institute of Hematology & Blood Diseases Hospital, China	marketed	Thrombopoietin receptor agonist	TPO receptor (MPLS)
Promacta	ELTROMBOPAG	Novartis	marketed	Thrombopoietin Receptor Agonist	Thrombopoietin receptor	2008-01-01
Nplate	ROMIPLOSTIM	Amgen	marketed	Thrombopoietin Receptor Agonist [EPC]	Thrombopoietin receptor	2008-01-01
rhTPO combined with Herombopag + CsA	rhTPO combined with Herombopag + CsA	Peking Union Medical College Hospital	marketed	Thrombopoietin receptor agonist combination with immunosuppressant	Thrombopoietin receptor (MPL); calcineurin (CsA target)
CsA+ATG+Herombopag	CsA+ATG+Herombopag	Peking Union Medical College Hospital	marketed	Immunosuppressive agent + thrombopoietin receptor agonist combination	Calcineurin (CsA); T lymphocytes (ATG); thrombopoietin receptor (eltrombopag)
Avatrombopag Oral Tablet	Avatrombopag Oral Tablet	Sobi, Inc.	marketed	Thrombopoietin receptor agonist	TPO receptor (c-Mpl)
CsA+Herombopag	CsA+Herombopag	Peking Union Medical College Hospital	marketed	Combination therapy: calcineurin inhibitor + thrombopoietin receptor agonist	Calcineurin (CsA); thrombopoietin receptor / MPL (herombopag)

Recent regulatory actions (last 90 days)

2026-03-16 — Promacta · FDA · approved · US · Novartis

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Thrombopoietin receptor agonist class)

Centro de Atencion e Investigacion Medica · 2 drugs in this class
Institute of Hematology & Blood Diseases Hospital, China · 2 drugs in this class
Jiangsu HengRui Medicine Co., Ltd. · 2 drugs in this class
Hvidovre University Hospital · 1 drug in this class
Kyowa Kirin Korea Co., Ltd. · 1 drug in this class
Peking Union Medical College Hospital · 1 drug in this class
PharmaEssentia Japan K.K. · 1 drug in this class
Qilu Pharmaceutical Co., Ltd. · 1 drug in this class
Shenyang Sunshine Pharmaceutical Co., LTD. · 1 drug in this class
Amgen · 1 drug in this class

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Cite this brief

Drug Landscape (2026). TPO-RAs — Competitive Intelligence Brief. https://druglandscape.com/ci/tpo-ras. Accessed 2026-05-14.

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