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Topotecan, dexamethasone, vincristine — Competitive Intelligence Brief
phase 3
Topoisomerase I inhibitor, Vinca alkaloid, Corticosteroid
Topoisomerase I, Tubulin
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Topotecan, dexamethasone, vincristine (Topotecan, dexamethasone, vincristine) — St. Jude Children's Research Hospital. Topotecan is a topoisomerase I inhibitor, vincristine is a vinca alkaloid that disrupts microtubule formation, and dexamethasone is a corticosteroid that suppresses inflammation and immune response.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Topotecan, dexamethasone, vincristine TARGET | Topotecan, dexamethasone, vincristine | St. Jude Children's Research Hospital | phase 3 | Topoisomerase I inhibitor, Vinca alkaloid, Corticosteroid | Topoisomerase I, Tubulin |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Topoisomerase I inhibitor, Vinca alkaloid, Corticosteroid class)
- St. Jude Children's Research Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Topotecan, dexamethasone, vincristine — Competitive Intelligence Brief. https://druglandscape.com/ci/topotecan-dexamethasone-vincristine. Accessed 2026-05-17.
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