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Topical capsaicin — Competitive Intelligence Brief
marketed
Topical analgesic; TRPV1 agonist
TRPV1 (transient receptor potential vanilloid 1)
Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Topical capsaicin (Topical capsaicin) — The University of Texas Health Science Center, Houston. Topical capsaicin activates and then desensitizes TRPV1 nociceptors, reducing the transmission of pain signals from the skin.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Topical capsaicin TARGET | Topical capsaicin | The University of Texas Health Science Center, Houston | marketed | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) | |
| Capsaicine low dose 0.04 % | Capsaicine low dose 0.04 % | University Hospital, Clermont-Ferrand | marketed | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) | |
| Qutenza Patch | Qutenza Patch | M.D. Anderson Cancer Center | marketed | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) | |
| Capsaicin 8% | Capsaicin 8% | Averitas Pharma, Inc. | marketed | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) | |
| Capsaicin Topical Cream | Capsaicin Topical Cream | Women and Infants Hospital of Rhode Island | marketed | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) | |
| NGX-4010 | NGX-4010 | NeurogesX | phase 3 | Topical analgesic; TRPV1 agonist | TRPV1 (transient receptor potential vanilloid 1) | |
| Intranasal capsaicin | Intranasal capsaicin | The University of Texas Health Science Center, Houston | phase 3 | TRPV1 agonist / Topical analgesic | TRPV1 (Transient Receptor Potential Vanilloid 1) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Topical analgesic; TRPV1 agonist class)
- Averitas Pharma, Inc. · 1 drug in this class
- M.D. Anderson Cancer Center · 1 drug in this class
- NeurogesX · 1 drug in this class
- The University of Texas Health Science Center, Houston · 1 drug in this class
- University Hospital, Clermont-Ferrand · 1 drug in this class
- Women and Infants Hospital of Rhode Island · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Topical capsaicin — Competitive Intelligence Brief. https://druglandscape.com/ci/topical-capsaicin. Accessed 2026-05-15.
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