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Topical capsaicin — Competitive Intelligence Brief

Topical capsaicin (Topical capsaicin) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topical analgesic; TRPV1 agonist. Area: Pain Management.

marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1) Pain Management Small molecule Live · refreshed every 30 min

Target snapshot

Topical capsaicin (Topical capsaicin) — The University of Texas Health Science Center, Houston. Topical capsaicin activates and then desensitizes TRPV1 nociceptors, reducing the transmission of pain signals from the skin.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Topical capsaicin TARGET Topical capsaicin The University of Texas Health Science Center, Houston marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)
Capsaicine low dose 0.04 % Capsaicine low dose 0.04 % University Hospital, Clermont-Ferrand marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)
Qutenza Patch Qutenza Patch M.D. Anderson Cancer Center marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)
Capsaicin 8% Capsaicin 8% Averitas Pharma, Inc. marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)
Capsaicin Topical Cream Capsaicin Topical Cream Women and Infants Hospital of Rhode Island marketed Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)
NGX-4010 NGX-4010 NeurogesX phase 3 Topical analgesic; TRPV1 agonist TRPV1 (transient receptor potential vanilloid 1)
Intranasal capsaicin Intranasal capsaicin The University of Texas Health Science Center, Houston phase 3 TRPV1 agonist / Topical analgesic TRPV1 (Transient Receptor Potential Vanilloid 1)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Topical analgesic; TRPV1 agonist class)

  1. Averitas Pharma, Inc. · 1 drug in this class
  2. M.D. Anderson Cancer Center · 1 drug in this class
  3. NeurogesX · 1 drug in this class
  4. The University of Texas Health Science Center, Houston · 1 drug in this class
  5. University Hospital, Clermont-Ferrand · 1 drug in this class
  6. Women and Infants Hospital of Rhode Island · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Topical capsaicin — Competitive Intelligence Brief. https://druglandscape.com/ci/topical-capsaicin. Accessed 2026-05-15.

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