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tolvaptan+torasemide — Competitive Intelligence Brief

tolvaptan+torasemide (tolvaptan+torasemide) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination diuretic (vasopressin V2 receptor antagonist + loop diuretic). Area: Cardiovascular / Hepatology.

marketed Combination diuretic (vasopressin V2 receptor antagonist + loop diuretic) Vasopressin V2 receptor (tolvaptan); Na-K-Cl cotransporter (torasemide) Cardiovascular / Hepatology Small molecule Live · refreshed every 30 min

Target snapshot

tolvaptan+torasemide (tolvaptan+torasemide) — Shanghai Chest Hospital. Tolvaptan blocks vasopressin V2 receptors to promote water excretion, while torasemide inhibits the Na-K-Cl cotransporter in the loop of Henle to increase sodium and water loss.

Comparator set

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
tolvaptan+torasemide TARGET tolvaptan+torasemide Shanghai Chest Hospital marketed Combination diuretic (vasopressin V2 receptor antagonist + loop diuretic) Vasopressin V2 receptor (tolvaptan); Na-K-Cl cotransporter (torasemide)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination diuretic (vasopressin V2 receptor antagonist + loop diuretic) class)

  1. Shanghai Chest Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). tolvaptan+torasemide — Competitive Intelligence Brief. https://druglandscape.com/ci/tolvaptan-torasemide. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing