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tolvaptan+torasemide — Competitive Intelligence Brief
marketed
Combination diuretic (vasopressin V2 receptor antagonist + loop diuretic)
Vasopressin V2 receptor (tolvaptan); Na-K-Cl cotransporter (torasemide)
Cardiovascular / Hepatology
Small molecule
Live · refreshed every 30 min
Target snapshot
tolvaptan+torasemide (tolvaptan+torasemide) — Shanghai Chest Hospital. Tolvaptan blocks vasopressin V2 receptors to promote water excretion, while torasemide inhibits the Na-K-Cl cotransporter in the loop of Henle to increase sodium and water loss.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| tolvaptan+torasemide TARGET | tolvaptan+torasemide | Shanghai Chest Hospital | marketed | Combination diuretic (vasopressin V2 receptor antagonist + loop diuretic) | Vasopressin V2 receptor (tolvaptan); Na-K-Cl cotransporter (torasemide) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination diuretic (vasopressin V2 receptor antagonist + loop diuretic) class)
- Shanghai Chest Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). tolvaptan+torasemide — Competitive Intelligence Brief. https://druglandscape.com/ci/tolvaptan-torasemide. Accessed 2026-06-10.
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