Who are Tolvaptan Tablets's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Samsca, Physulime, Vaprisol In 5% Dextrose In Plastic Container, tolvaptan+torasemide, Vasopressin administration, OPC-41061.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-15 · How we verify

Tolvaptan Tablets — Competitive Intelligence Brief

Tolvaptan Tablets (Tolvaptan Tablets) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Vasopressin receptor antagonist. Area: Cardiovascular.

phase 3 Vasopressin receptor antagonist V2 receptor Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Tolvaptan Tablets (Tolvaptan Tablets) — Institute of Liver and Biliary Sciences, India. Tolvaptan is a selective, competitive antagonist of the vasopressin V2 receptor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Tolvaptan Tablets TARGET	Tolvaptan Tablets	Institute of Liver and Biliary Sciences, India	phase 3	Vasopressin receptor antagonist	V2 receptor
Samsca	TOLVAPTAN	Otsuka	marketed	Vasopressin V2 Receptor Antagonist [EPC]	Vasopressin V2 receptor	2009-01-01
Physulime	MOZAVAPTAN	Otsuka Pharmaceutical Co., Ltd.	marketed	mozavaptan	Vasopressin V2 receptor	2006-01-01
Vaprisol In 5% Dextrose In Plastic Container	CONIVAPTAN	Cumberland	marketed	Vasopressin Receptor Antagonist	Vasopressin V2 receptor	2005-01-01
tolvaptan+torasemide	tolvaptan+torasemide	Shanghai Chest Hospital	marketed	Combination diuretic (vasopressin V2 receptor antagonist + loop diuretic)	Vasopressin V2 receptor (tolvaptan); Na-K-Cl cotransporter (torasemide)
Vasopressin administration	Vasopressin administration	Assistance Publique Hopitaux De Marseille	phase 3	Vasopressin receptor agonist	V1A and V2 receptors
OPC-41061	OPC-41061	Otsuka Pharmaceutical Co., Ltd.	phase 3	Vasopressin V2 receptor antagonist (vaptан)	Vasopressin V2 receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Vasopressin receptor antagonist class)

Institute of Liver and Biliary Sciences, India · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tolvaptan Tablets — Competitive Intelligence Brief. https://druglandscape.com/ci/tolvaptan-tablets. Accessed 2026-05-15.

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