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TNFR:Fc — Competitive Intelligence Brief
phase 3
TNF inhibitor
TNF
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
TNFR:Fc (TNFR:Fc) — National Eye Institute (NEI). TNFR:Fc is a fusion protein that binds to tumor necrosis factor (TNF) and prevents it from interacting with its receptors on cell surfaces.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| TNFR:Fc TARGET | TNFR:Fc | National Eye Institute (NEI) | phase 3 | TNF inhibitor | TNF | |
| Cimzia | CERTOLIZUMAB PEGOL | UCB | marketed | Tumor Necrosis Factor Blocker [EPC] | TNFα | 2008-01-01 |
| Humira | ADALIMUMAB | AbbVie | marketed | TNF blocker | Tumor Necrosis Factor-alpha (TNF-alpha) | 2002-01-01 |
| Abrilada | Adalimumab-Afzb | AbbVie | marketed | TNF blocker | Tumor necrosis factor-alpha (TNF-alpha) | 2002-01-01 |
| Remicade | Infliximab-Dyyb | Johnson & Johnson | marketed | TNF blocker | Tumor Necrosis Factor alpha (TNFα) | 1998-01-01 |
| Infliximab-Dyyb | Infliximab-Dyyb | Asan Medical Center | marketed | TNF-alpha inhibitor; monoclonal antibody | TNF-alpha (TNFα) | |
| Etanercept + Acitretin | Etanercept + Acitretin | Pfizer | marketed | TNF inhibitor + retinoid combination | TNF-α receptor (p75/p55) + retinoid X receptor (RXR) and retinoic acid receptor (RAR) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (TNF inhibitor class)
- University Hospital, Montpellier · 2 drugs in this class
- Amgen · 1 drug in this class
- Biogen · 1 drug in this class
- Centre Hospitalier Universitaire de Saint Etienne · 1 drug in this class
- National Eye Institute (NEI) · 1 drug in this class
- Abbott · 1 drug in this class
- Spanish Clinical Pharmacology Society · 1 drug in this class
- Takeda · 1 drug in this class
- University Health Network, Toronto · 1 drug in this class
- University Hospital, Ghent · 1 drug in this class
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Cite this brief
Drug Landscape (2026). TNFR:Fc — Competitive Intelligence Brief. https://druglandscape.com/ci/tnfr-fc. Accessed 2026-05-17.
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