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TNFR:Fc — Competitive Intelligence Brief

TNFR:Fc (TNFR:Fc) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: TNF inhibitor. Area: Immunology.

phase 3 TNF inhibitor TNF Immunology Small molecule Live · refreshed every 30 min

Target snapshot

TNFR:Fc (TNFR:Fc) — National Eye Institute (NEI). TNFR:Fc is a fusion protein that binds to tumor necrosis factor (TNF) and prevents it from interacting with its receptors on cell surfaces.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
TNFR:Fc TARGET TNFR:Fc National Eye Institute (NEI) phase 3 TNF inhibitor TNF
Cimzia CERTOLIZUMAB PEGOL UCB marketed Tumor Necrosis Factor Blocker [EPC] TNFα 2008-01-01
Humira ADALIMUMAB AbbVie marketed TNF blocker Tumor Necrosis Factor-alpha (TNF-alpha) 2002-01-01
Abrilada Adalimumab-Afzb AbbVie marketed TNF blocker Tumor necrosis factor-alpha (TNF-alpha) 2002-01-01
Remicade Infliximab-Dyyb Johnson & Johnson marketed TNF blocker Tumor Necrosis Factor alpha (TNFα) 1998-01-01
Infliximab-Dyyb Infliximab-Dyyb Asan Medical Center marketed TNF-alpha inhibitor; monoclonal antibody TNF-alpha (TNFα)
Etanercept + Acitretin Etanercept + Acitretin Pfizer marketed TNF inhibitor + retinoid combination TNF-α receptor (p75/p55) + retinoid X receptor (RXR) and retinoic acid receptor (RAR)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (TNF inhibitor class)

  1. University Hospital, Montpellier · 2 drugs in this class
  2. Amgen · 1 drug in this class
  3. Biogen · 1 drug in this class
  4. Centre Hospitalier Universitaire de Saint Etienne · 1 drug in this class
  5. National Eye Institute (NEI) · 1 drug in this class
  6. Abbott · 1 drug in this class
  7. Spanish Clinical Pharmacology Society · 1 drug in this class
  8. Takeda · 1 drug in this class
  9. University Health Network, Toronto · 1 drug in this class
  10. University Hospital, Ghent · 1 drug in this class

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Cite this brief

Drug Landscape (2026). TNFR:Fc — Competitive Intelligence Brief. https://druglandscape.com/ci/tnfr-fc. Accessed 2026-05-17.

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