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TLK286 in Combination with Carboplatin — Competitive Intelligence Brief
phase 3
Histone deacetylase inhibitor
Histone deacetylase
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
TLK286 in Combination with Carboplatin (TLK286 in Combination with Carboplatin) — Telik. TLK286 is a histone deacetylase inhibitor that works by blocking the activity of histone deacetylases, leading to the inhibition of cancer cell growth and induction of apoptosis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| TLK286 in Combination with Carboplatin TARGET | TLK286 in Combination with Carboplatin | Telik | phase 3 | Histone deacetylase inhibitor | Histone deacetylase | |
| Farydak | PANOBINOSTAT | Secura | marketed | Histone Deacetylase Inhibitor | Histone deacetylase 4 | 2015-01-01 |
| Beleodaq | belinostat | Acrotech Biopharma | marketed | Histone Deacetylase Inhibitor [EPC] | Histone deacetylase 1 | 2014-01-01 |
| Treanda | BENDAMUSTINE | Baxter | marketed | Alkylating Drug | Histone deacetylase 6 | 2008-01-01 |
| Zolinza | VORINOSTAT | Merck & Co. | marketed | Histone Deacetylase Inhibitor [EPC] | Histone deacetylase 6 | 2006-01-01 |
| Daunorubicin Hydrochloride | daunorubicin | Meiji Seika Pharma Co., Ltd | marketed | Anthracycline Topoisomerase Inhibitor | Histone deacetylase 6 | 1979-01-01 |
| Depakene | valproic acid | Generic (originally Abbott/AbbVie) | marketed | Anti-epileptic Agent [EPC] | Alcohol dehydrogenase [NADP(+)], Histone deacetylase 1, Histone deacetylase 2 | 1978-02-28 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Histone deacetylase inhibitor class)
- Celgene · 1 drug in this class
- Chengdu Zenitar Biomedical Technology Co., Ltd · 1 drug in this class
- Evopoint Biosciences Inc. · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Medical University of Vienna · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- NCIC Clinical Trials Group · 1 drug in this class
- PharmaMar · 1 drug in this class
- Telik · 1 drug in this class
- Tianjin Medical University Cancer Institute and Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). TLK286 in Combination with Carboplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/tlk286-in-combination-with-carboplatin. Accessed 2026-05-17.
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