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Thienopyridine (open-label) — Competitive Intelligence Brief
marketed
P2Y12 receptor antagonist / Antiplatelet agent
P2Y12 receptor
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Thienopyridine (open-label) (Thienopyridine (open-label)) — VA Office of Research and Development. Thienopyridines inhibit platelet aggregation by blocking the P2Y12 adenosine diphosphate receptor on platelets.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Thienopyridine (open-label) TARGET | Thienopyridine (open-label) | VA Office of Research and Development | marketed | P2Y12 receptor antagonist / Antiplatelet agent | P2Y12 receptor | |
| Prasugrel loading | Prasugrel loading | Azienda Policlinico Umberto I | marketed | P2Y12 receptor antagonist (thienopyridine) | P2Y12 receptor | |
| ASA plus Clopidogrel | ASA plus Clopidogrel | Texas Cardiac Arrhythmia Research Foundation | marketed | Dual antiplatelet agent | COX-1 (aspirin); P2Y12 receptor (clopidogrel) | |
| Aspirin and Clopidogrel | Aspirin and Clopidogrel | Assistance Publique - Hôpitaux de Paris | marketed | Antiplatelet agent (dual therapy) | Cyclooxygenase (COX) and P2Y12 receptor | |
| rivaroxaban and ticagrel therapy | rivaroxaban and ticagrel therapy | Beijing Anzhen Hospital | marketed | Anticoagulant and antiplatelet combination therapy | Factor Xa (rivaroxaban); P2Y12 receptor (ticagrelor) | |
| CYP2C19 Genotype Guided DAPT | CYP2C19 Genotype Guided DAPT | Zunyi Medical College | marketed | Pharmacogenomic-guided antiplatelet therapy strategy | CYP2C19 enzyme; P2Y12 receptor (indirect) | |
| extended postimplantation dual antiplatelet therapy | extended postimplantation dual antiplatelet therapy | National Institute of Cardiology, Warsaw, Poland | marketed | Antiplatelet therapy combination | Platelet aggregation pathways (cyclooxygenase and P2Y12 receptor) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (P2Y12 receptor antagonist / Antiplatelet agent class)
- Centre hospitalier de l'Université de Montréal (CHUM) · 1 drug in this class
- Jeil Pharmaceutical Co., Ltd. · 1 drug in this class
- University of Florida · 1 drug in this class
- VA Office of Research and Development · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Thienopyridine (open-label) — Competitive Intelligence Brief. https://druglandscape.com/ci/thienopyridine-open-label. Accessed 2026-06-09.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing