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TGRX-678 — Competitive Intelligence Brief

TGRX-678 (TGRX-678) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: SGLT2 inhibitor. Area: Diabetes.

phase 3 SGLT2 inhibitor SGLT2 Diabetes Small molecule Live · refreshed every 30 min

Target snapshot

TGRX-678 (TGRX-678) — Shenzhen TargetRx Co., Ltd.. TGRX-678 is a small molecule that targets the SGLT2 receptor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
TGRX-678 TARGET TGRX-678 Shenzhen TargetRx Co., Ltd. phase 3 SGLT2 inhibitor SGLT2
Brenzavvy BEXAGLIFLOZIN Theracosbio marketed Sodium-Glucose Cotransporter 2 Inhibitor [EPC] SGLT2 2023-01-01
Jardiance empagliflozin Boehringer Ingelheim marketed Sodium-Glucose Cotransporter 2 Inhibitor [EPC] SGLT2 2014-01-01
Antihyperglycemic Medication Antihyperglycemic Medication Merck Sharp & Dohme LLC marketed SGLT2 inhibitor SGLT2 (sodium-glucose cotransporter 2)
Dapagliflozin/Pioglitazone Dapagliflozin/Pioglitazone Boryung Pharmaceutical Co., Ltd marketed SGLT2 inhibitor / Thiazolidinedione combination SGLT2 / PPAR-γ
SGLT2i+Metformin+Linagliptin SGLT2i+Metformin+Linagliptin Huazhong University of Science and Technology marketed Combination antidiabetic agent (SGLT2 inhibitor + biguanide + DPP-4 inhibitor) SGLT2 transporter, mitochondrial complex I (metformin), dipeptidyl peptidase-4
Insulin/Canaglifozin Insulin/Canaglifozin University of Campania Luigi Vanvitelli marketed Insulin + SGLT2 inhibitor combination Insulin receptor; SGLT2 (sodium-glucose cotransporter 2)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (SGLT2 inhibitor class)

  1. Daewon Pharmaceutical Co., Ltd. · 13 drugs in this class
  2. Qilu Pharmaceutical Co., Ltd. · 10 drugs in this class
  3. Takeda · 10 drugs in this class
  4. Taejoon Pharmaceutical Co., Ltd. · 9 drugs in this class
  5. Hanmi Pharmaceutical Company Limited · 9 drugs in this class
  6. Addpharma Inc. · 9 drugs in this class
  7. GlaxoSmithKline · 7 drugs in this class
  8. AO GENERIUM · 7 drugs in this class
  9. Merck Sharp & Dohme LLC · 7 drugs in this class
  10. Nobelpharma · 6 drugs in this class

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Cite this brief

Drug Landscape (2026). TGRX-678 — Competitive Intelligence Brief. https://druglandscape.com/ci/tgrx-678. Accessed 2026-05-13.

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