Who are TEPEZZA's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Increlex, Increlex, Tepezza.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-06-10 · How we verify

TEPEZZA — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

TEPEZZA (TEPROTUMUMAB-TRBW) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Insulin-like Growth Factor-1 Receptor Inhibitor [EPC]. Area: Metabolic.

marketed Insulin-like Growth Factor-1 Receptor Inhibitor [EPC] Insulin-like growth factor 1 receptor Metabolic Live · refreshed every 30 min

Target snapshot

TEPEZZA (TEPROTUMUMAB-TRBW) — HORIZON THERAPEUTICS IRELAND.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
TEPEZZA TARGET	TEPROTUMUMAB-TRBW	HORIZON THERAPEUTICS IRELAND	marketed	Insulin-like Growth Factor-1 Receptor Inhibitor [EPC]	Insulin-like growth factor 1 receptor
Increlex	MECASERMIN	Ipsen Inc	marketed		Insulin-like growth factor 1 receptor	2005-01-01
Increlex	Increlex	Children's Hospital Medical Center, Cincinnati	marketed		Insulin receptor, Insulin-like growth factor 1 receptor
Tepezza	TEPROTUMUMAB	Horizon Therapeutics Ireland	marketed	Insulin-like Growth Factor-1 Receptor Inhibitor [EPC]	IGF-1R	2020-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Insulin-like Growth Factor-1 Receptor Inhibitor [EPC] class)

HORIZON THERAPEUTICS IRELAND · 1 drug in this class
Horizon Therapeutics Ireland · 1 drug in this class

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Cite this brief

Drug Landscape (2026). TEPEZZA — Competitive Intelligence Brief. https://druglandscape.com/ci/teprotumumab-trbw. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing