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Tenofovir + lamivudine + raltegravir — Competitive Intelligence Brief

Tenofovir + lamivudine + raltegravir (Tenofovir + lamivudine + raltegravir) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NRTI + INSTI. Area: Infectious Diseases.

phase 3 NRTI + INSTI HIV integrase Infectious Diseases Small molecule Live · refreshed every 30 min

Target snapshot

Tenofovir + lamivudine + raltegravir (Tenofovir + lamivudine + raltegravir) — ANRS, Emerging Infectious Diseases. Tenofovir and lamivudine are nucleoside reverse transcriptase inhibitors (NRTIs) that block HIV replication by inhibiting viral DNA synthesis. Raltegravir is an integrase strand transfer inhibitor (INSTI) that blocks HIV replication by inhibiting viral integration into the host genome.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Tenofovir + lamivudine + raltegravir TARGET Tenofovir + lamivudine + raltegravir ANRS, Emerging Infectious Diseases phase 3 NRTI + INSTI HIV integrase
ELV/COBI/FTC/TAF ELV/COBI/FTC/TAF Fundacion SEIMC-GESIDA marketed Antiretroviral combination therapy (integrase inhibitor + NRTI + NtRTI + pharmacokinetic booster) HIV integrase, HIV reverse transcriptase
DTG/3TC/ABC + ELV/COBI/FTC/TAF DTG/3TC/ABC + ELV/COBI/FTC/TAF Fundacion SEIMC-GESIDA marketed Antiretroviral combination therapy (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) HIV integrase, HIV reverse transcriptase
Switch to DTG + 3TC Switch to DTG + 3TC Hospitales Universitarios Virgen del Rocío marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
bictegravir/emtricitabine/tenofovir alafenamide bictegravir/emtricitabine/tenofovir alafenamide Midland Research Group, Inc. marketed Antiretroviral combination (integrase inhibitor + nucleoside reverse transcriptase inhibitors) HIV integrase, HIV reverse transcriptase
dolutegravir/abacavir/lamivudine dolutegravir/abacavir/lamivudine University College Dublin marketed Antiretroviral combination (INSTI + NRTIs) HIV integrase, HIV reverse transcriptase
Long-acting Cabotegravir injection Long-acting Cabotegravir injection MU-JHU CARE marketed Integrase strand transfer inhibitor (INSTI) HIV integrase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NRTI + INSTI class)

  1. ANRS, Emerging Infectious Diseases · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tenofovir + lamivudine + raltegravir — Competitive Intelligence Brief. https://druglandscape.com/ci/tenofovir-lamivudine-raltegravir. Accessed 2026-05-16.

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