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Temozolomide + TACE — Competitive Intelligence Brief
phase 3
alkylating agent
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Temozolomide + TACE (Temozolomide + TACE) — Taizhou Hanzhong biomedical co. LTD. Temozolomide is an alkylating agent that works by interfering with DNA replication in cancer cells, while TACE is a minimally invasive procedure that involves the insertion of a catheter to deliver chemotherapy directly to the tumor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Temozolomide + TACE TARGET | Temozolomide + TACE | Taizhou Hanzhong biomedical co. LTD | phase 3 | alkylating agent | ||
| Paraplatin | Carboplatin | MYLAN SEIYAKU Ltd | marketed | Platinum-containing alkylating agent | DNA | 1989-01-01 |
| Cytoxan (Lyophilized) | cyclophosphamide | Baxter | marketed | Alkylating agent | Tumor cell DNA | 1959-01-01 |
| Standard of Care: Cyclophosphamide | Standard of Care: Cyclophosphamide | H. Lee Moffitt Cancer Center and Research Institute | marketed | Alkylating agent | DNA | |
| Platinum-Based Chemotherapy | Platinum-Based Chemotherapy | Genprex, Inc. | marketed | Platinum-based alkylating agent | DNA | |
| Cyclophosphamide (CYC) | Cyclophosphamide (CYC) | Hansa Biopharma AB | marketed | Alkylating agent | DNA | |
| CYC | CYC | Italian Sarcoma Group | marketed | Alkylating agent | DNA |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Cytoxan (Lyophilized) · 9662342 · Formulation · US
- — Cytoxan (Lyophilized) · 10849916 · Formulation · US
- — Cytoxan (Lyophilized) · 11382923 · Formulation · US
- — Cytoxan (Lyophilized) · 12329767 · Formulation · US
- — Cytoxan (Lyophilized) · 10993952 · Formulation · US
Sponsor landscape (alkylating agent class)
- Alliance for Clinical Trials in Oncology · 2 drugs in this class
- Assistance Publique - Hôpitaux de Paris · 1 drug in this class
- Radiation Therapy Oncology Group · 1 drug in this class
- Taizhou Hanzhong biomedical co. LTD · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Temozolomide + TACE — Competitive Intelligence Brief. https://druglandscape.com/ci/temozolomide-tace. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing