Who are TEGAFUR URACIL - FOLINIC ACID's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Xeloda, Fudr, Folic Acid, Capecitabine (Xeloda®), Pemetrexed + oral folinic acid rescue, Flutron.

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Last reviewed 2026-05-18 · How we verify

TEGAFUR URACIL - FOLINIC ACID — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

TEGAFUR URACIL - FOLINIC ACID (TEGAFUR URACIL - FOLINIC ACID) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimetabolite. Area: Oncology.

phase 3 Antimetabolite Thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

TEGAFUR URACIL - FOLINIC ACID (TEGAFUR URACIL - FOLINIC ACID) — Centre Oscar Lambret. Tegafur uracil combined with folinic acid enhances the cytotoxic effects of 5-fluorouracil by increasing its intracellular concentration and prolonging its action.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
TEGAFUR URACIL - FOLINIC ACID TARGET	TEGAFUR URACIL - FOLINIC ACID	Centre Oscar Lambret	phase 3	Antimetabolite	Thymidylate synthase
Xeloda	capecitabine	Cheplapharm	marketed	Nucleoside Metabolic Inhibitor [EPC]	Thymidylate synthase	1998-01-01
Fudr	FLOXURIDINE		marketed	Antimetabolite [EPC]	Thymidylate synthase	1970-01-01
Folic Acid	FOLIC ACID	Pfizer	marketed	Vitamin C [EPC]	Thymidylate synthase	1946-01-01
Capecitabine (Xeloda®)	Capecitabine (Xeloda®)	National Cancer Center, Korea	marketed	Fluoropyrimidine antimetabolite	Thymidylate synthase
Pemetrexed + oral folinic acid rescue	Pemetrexed + oral folinic acid rescue	Radboud University Medical Center	marketed	Antifolate antimetabolite	Thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase
Flutron	DOXIFLURIDINE		marketed	doxifluridine	Thymidylate synthase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimetabolite class)

Grupo Espanol Multidisciplinario del Cancer Digestivo · 2 drugs in this class
NRG Oncology · 2 drugs in this class
Bristol-Myers Squibb · 1 drug in this class
EMD Serono Research & Development Institute, Inc. · 1 drug in this class
GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
Hoffmann-La Roche · 1 drug in this class
Centre Oscar Lambret · 1 drug in this class
Iwate Medical University · 1 drug in this class
Janssen Research & Development, LLC · 1 drug in this class
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · 1 drug in this class

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Cite this brief

Drug Landscape (2026). TEGAFUR URACIL - FOLINIC ACID — Competitive Intelligence Brief. https://druglandscape.com/ci/tegafur-uracil-folinic-acid. Accessed 2026-05-18.

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