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tbo-filgrastim — Competitive Intelligence Brief
Target snapshot
tbo-filgrastim (tbo-filgrastim) — Teva Branded Pharmaceutical Products R&D, Inc.. 12.1 Mechanism of Action Tbo-filgrastim is a human granulocyte colony-stimulating factor (G-CSF) produced by recombinant DNA technology. Tbo-filgrastim binds to G-CSF receptors and stimulates proliferation of neutrophils. G-CSF is known to stimulate differentiation commitment and some end-cell functional activation, which increases neutrophil counts and activity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| tbo-filgrastim TARGET | tbo-filgrastim | Teva Branded Pharmaceutical Products R&D, Inc. | discontinued | Leukocyte Growth Factor [EPC] | ||
| Rolvedon | EFLAPEGRASTIM | Spectrum Pharms | marketed | Leukocyte Growth Factor [EPC] | Granulocyte colony-stimulating factor receptor | 2022-01-01 |
| Neulasta | PEGFILGRASTIM | Amgen | marketed | Leukocyte Growth Factor [EPC] | Granulocyte colony-stimulating factor receptor | 2002-01-01 |
| Neupogen | Filgrastim-Aafi | Amgen | marketed | Colony-stimulating factor (CSF); leukocyte growth factor | G-CSF receptor (granulocyte colony-stimulating factor receptor) | 1991-01-01 |
| FILGRASTIM | FILGRASTIM | marketed | Leukocyte Growth Factor [EPC] | Specific cell surface receptors on hematopoietic cells | 1991-01-01 | |
| Leukine | SARGRAMOSTIM | Berlex Labs | marketed | Leukocyte Growth Factor [EPC] | Granulocyte macrophage colony-stimulating factor receptor | 1991-01-01 |
| FYLNETRA | PEGFILGRASTIM-PBBK | KASHIV BIOSCIENCES LLC | marketed | Leukocyte Growth Factor [EPC] | specific cell surface receptors |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Leukocyte Growth Factor [EPC] class)
- KASHIV BIOSCIENCES LLC · 2 drugs in this class
- Amgen · 1 drug in this class
- Berlex Labs · 1 drug in this class
- EVIVE BIOTECHNOLOGY · 1 drug in this class
- FRESENIUS KABI USA · 1 drug in this class
- LUPIN LTD · 1 drug in this class
- MYLAN GMBH · 1 drug in this class
- SANDOZ INC · 1 drug in this class
- SPECTRUM PHARMS · 1 drug in this class
- Spectrum Pharms · 1 drug in this class
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Cite this brief
Drug Landscape (2026). tbo-filgrastim — Competitive Intelligence Brief. https://druglandscape.com/ci/tbo-filgrastim. Accessed 2026-06-10.
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