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Tamoxifen (open label) — Competitive Intelligence Brief

Tamoxifen (open label) (Tamoxifen (open label)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Selective estrogen receptor modulator (SERM). Area: Oncology.

marketed Selective estrogen receptor modulator (SERM) Estrogen receptor alpha (ERα) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Tamoxifen (open label) (Tamoxifen (open label)) — Oregon Health and Science University. Tamoxifen is a selective estrogen receptor modulator (SERM) that blocks estrogen signaling in breast tissue by competitively binding to estrogen receptors.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Tamoxifen (open label) TARGET Tamoxifen (open label) Oregon Health and Science University marketed Selective estrogen receptor modulator (SERM) Estrogen receptor alpha (ERα)
fenofibrate and tibolone fenofibrate and tibolone Keogh Institute for Medical Research marketed Fibrate + Selective Estrogen Receptor Modulator (SERM) PPAR-α (fenofibrate); Estrogen receptor, progesterone receptor, androgen receptor (tibolone)
raloxifene HCI and alendronate Na raloxifene HCI and alendronate Na Eli Lilly and Company marketed Selective estrogen receptor modulator (SERM) + bisphosphonate combination Estrogen receptor (raloxifene); osteoclast farnesyl pyrophosphate synthase (alendronate)
E2Nomac E2Nomac Sydney Centre for Reproductive Health Research marketed Selective Estrogen Receptor Modulator (SERM) Estrogen receptor (ER-α/ER-β)
Toremifene; Anastrozole Toremifene; Anastrozole Peking Union Medical College Hospital marketed Selective estrogen receptor modulator (SERM) + aromatase inhibitor (AI) Estrogen receptor (ER); aromatase (CYP19A1)
Low Dose Clomiphencitrat Low Dose Clomiphencitrat University Hospital, Basel, Switzerland marketed Selective estrogen receptor modulator (SERM) Estrogen receptor (ER-α and ER-β)
Tamoxifen Oral Tablet Tamoxifen Oral Tablet Samsung Medical Center marketed Selective estrogen receptor modulator (SERM) Estrogen receptor alpha (ERα)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Selective estrogen receptor modulator (SERM) class)

  1. University Hospital, Basel, Switzerland · 2 drugs in this class
  2. AstraZeneca · 2 drugs in this class
  3. Estetra · 1 drug in this class
  4. Fundació Privada Eugin · 1 drug in this class
  5. H. Lee Moffitt Cancer Center and Research Institute · 1 drug in this class
  6. National Taiwan University Hospital · 1 drug in this class
  7. Oregon Health and Science University · 1 drug in this class
  8. Samsung Medical Center · 1 drug in this class
  9. Shandong Suncadia Medicine Co., Ltd. · 1 drug in this class
  10. Sheba Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tamoxifen (open label) — Competitive Intelligence Brief. https://druglandscape.com/ci/tamoxifen-open-label. Accessed 2026-05-17.

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