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Tamoxifen + Aminoglutethimide — Competitive Intelligence Brief

Tamoxifen + Aminoglutethimide (Tamoxifen + Aminoglutethimide) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: SERM and CYP11A1 inhibitor. Area: Oncology.

phase 3 SERM and CYP11A1 inhibitor estrogen receptor Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Tamoxifen + Aminoglutethimide (Tamoxifen + Aminoglutethimide) — Austrian Breast & Colorectal Cancer Study Group. Tamoxifen acts as a selective estrogen receptor modulator (SERM) to inhibit estrogen's action in breast tissue, while aminoglutethimide inhibits the enzyme CYP11A1, which is involved in the synthesis of steroids, including estrogen.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Tamoxifen + Aminoglutethimide TARGET Tamoxifen + Aminoglutethimide Austrian Breast & Colorectal Cancer Study Group phase 3 SERM and CYP11A1 inhibitor estrogen receptor
Orserdu ELACESTRANT Stemline Therap marketed Estrogen Receptor Antagonist [EPC] Estrogen receptor 2023-01-01
Nextstellis ESTETROL Mayne Pharma marketed Estrogen Estrogen receptor 2021-01-01
Cerianna FLUOROESTRADIOL F-18 GE HealthCare marketed Radioactive Diagnostic Agent [EPC] Estrogen receptor 2020-01-01
Duavee conjugated-estrogens-bazedoxifene Pfizer marketed Estrogen [EPC] estrogen receptors α and β 2013-01-01
Osphena OSPEMIFENE Duchesnay marketed Estrogen Agonist/Antagonist [EPC] Estrogen receptor beta 2013-01-01
Duavee BAZEDOXIFENE Wyeth Pharms Pfizer marketed Estrogen [EPC] estrogen receptors (ER) α and β 2013-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (SERM and CYP11A1 inhibitor class)

  1. Austrian Breast & Colorectal Cancer Study Group · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tamoxifen + Aminoglutethimide — Competitive Intelligence Brief. https://druglandscape.com/ci/tamoxifen-aminoglutethimide. Accessed 2026-05-16.

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