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Tafenoquine Oral Tablet — Competitive Intelligence Brief

Tafenoquine Oral Tablet (Tafenoquine Oral Tablet) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: 8-aminoquinoline. Area: Infectious Diseases.

phase 3 8-aminoquinoline dihydroorotate dehydrogenase Infectious Diseases Small molecule Live · refreshed every 30 min

Target snapshot

Tafenoquine Oral Tablet (Tafenoquine Oral Tablet) — State University of New York - Upstate Medical University. Tafenoquine is an antimalarial drug that works by targeting the Plasmodium parasite's heme detoxification pathway.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Tafenoquine Oral Tablet TARGET Tafenoquine Oral Tablet State University of New York - Upstate Medical University phase 3 8-aminoquinoline dihydroorotate dehydrogenase
Aubagio TERIFLUNOMIDE Sanofi marketed Pyrimidine Synthesis Inhibitor [EPC] dihydroorotate dehydrogenase 2012-01-01
Leflunomide 10 milligram (MG) Leflunomide 10 milligram (MG) P. Verschueren marketed DHODH inhibitor; disease-modifying antirheumatic drug (DMARD) Dihydroorotate dehydrogenase (DHODH)
FLUNIXIN FLUNIXIN marketed Dihydroorotate dehydrogenase (quinone), mitochondrial
Teriflunomide HMR1726 Teriflunomide HMR1726 Sanofi marketed Dihydroorotate dehydrogenase inhibitor; immunosuppressant Dihydroorotate dehydrogenase (DHODH)
Leflunomide plus Methotrexate Leflunomide plus Methotrexate Bangladesh Medical University marketed Disease-modifying antirheumatic drug (DMARD) combination Dihydroorotate dehydrogenase (leflunomide); Dihydrofolate reductase (methotrexate)
Leflunomide(LEF) Leflunomide(LEF) Nanjing Children's Hospital marketed Immunosuppressant; DHODH inhibitor Dihydroorotate dehydrogenase (DHODH)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (8-aminoquinoline class)

  1. GlaxoSmithKline · 1 drug in this class
  2. London School of Hygiene and Tropical Medicine · 1 drug in this class
  3. State University of New York - Upstate Medical University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tafenoquine Oral Tablet — Competitive Intelligence Brief. https://druglandscape.com/ci/tafenoquine-oral-tablet. Accessed 2026-05-16.

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