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Tafenoquine Oral Tablet — Competitive Intelligence Brief
phase 3
8-aminoquinoline
dihydroorotate dehydrogenase
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
Tafenoquine Oral Tablet (Tafenoquine Oral Tablet) — State University of New York - Upstate Medical University. Tafenoquine is an antimalarial drug that works by targeting the Plasmodium parasite's heme detoxification pathway.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Tafenoquine Oral Tablet TARGET | Tafenoquine Oral Tablet | State University of New York - Upstate Medical University | phase 3 | 8-aminoquinoline | dihydroorotate dehydrogenase | |
| Aubagio | TERIFLUNOMIDE | Sanofi | marketed | Pyrimidine Synthesis Inhibitor [EPC] | dihydroorotate dehydrogenase | 2012-01-01 |
| Leflunomide 10 milligram (MG) | Leflunomide 10 milligram (MG) | P. Verschueren | marketed | DHODH inhibitor; disease-modifying antirheumatic drug (DMARD) | Dihydroorotate dehydrogenase (DHODH) | |
| FLUNIXIN | FLUNIXIN | marketed | Dihydroorotate dehydrogenase (quinone), mitochondrial | |||
| Teriflunomide HMR1726 | Teriflunomide HMR1726 | Sanofi | marketed | Dihydroorotate dehydrogenase inhibitor; immunosuppressant | Dihydroorotate dehydrogenase (DHODH) | |
| Leflunomide plus Methotrexate | Leflunomide plus Methotrexate | Bangladesh Medical University | marketed | Disease-modifying antirheumatic drug (DMARD) combination | Dihydroorotate dehydrogenase (leflunomide); Dihydrofolate reductase (methotrexate) | |
| Leflunomide(LEF) | Leflunomide(LEF) | Nanjing Children's Hospital | marketed | Immunosuppressant; DHODH inhibitor | Dihydroorotate dehydrogenase (DHODH) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (8-aminoquinoline class)
- GlaxoSmithKline · 1 drug in this class
- London School of Hygiene and Tropical Medicine · 1 drug in this class
- State University of New York - Upstate Medical University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Tafenoquine Oral Tablet — Competitive Intelligence Brief. https://druglandscape.com/ci/tafenoquine-oral-tablet. Accessed 2026-05-16.
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