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Tacrolimus/MMF — Competitive Intelligence Brief

Tacrolimus/MMF (Tacrolimus/MMF) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Immunosuppressant combination. Area: Immunology / Transplantation.

marketed Immunosuppressant combination Calcineurin (tacrolimus); IMPDH type II (MMF) Immunology / Transplantation Small molecule Live · refreshed every 30 min

Target snapshot

Tacrolimus/MMF (Tacrolimus/MMF) — University of Miami. Tacrolimus and mycophenolate mofetil (MMF) together suppress T-cell and B-cell activation to prevent organ rejection after transplantation.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Tacrolimus/MMF TARGET Tacrolimus/MMF University of Miami marketed Immunosuppressant combination Calcineurin (tacrolimus); IMPDH type II (MMF)
Ciclosporin and Mycophenolate-mofetil Ciclosporin and Mycophenolate-mofetil University of Giessen marketed Immunosuppressant combination Calcineurin (ciclosporin); IMPDH type II (mycophenolate mofetil)
Mycophenolate to sirolimus switch Mycophenolate to sirolimus switch London Health Sciences Centre marketed Immunosuppressant combination therapy mTOR (sirolimus component); IMPDH (mycophenolate component being replaced)
LCP-tacrolimus QD + MMF QD then MMF QD LCP-tacrolimus QD + MMF QD then MMF QD University Hospital, Limoges marketed Calcineurin inhibitor + antimetabolite immunosuppressant combination Calcineurin (tacrolimus); inosine monophosphate dehydrogenase type II (MMF)
XR-tacrolimus QD + MMF BID XR-tacrolimus QD + MMF BID University Hospital, Limoges marketed Calcineurin inhibitor + Antimetabolite immunosuppressant combination Calcineurin (tacrolimus); IMPDH type II (mycophenolate mofetil)
XR-tacrolimus QD + MMF BID then MMF QD XR-tacrolimus QD + MMF BID then MMF QD University Hospital, Limoges marketed Calcineurin inhibitor + Antimetabolite immunosuppressant combination Calcineurin (tacrolimus); Inosine monophosphate dehydrogenase (mycophenolate mofetil)
infliximab+azathioprine infliximab+azathioprine Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW marketed TNF-α inhibitor + immunosuppressant combination TNF-α receptor (infliximab); purine metabolism (azathioprine)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Immunosuppressant combination class)

  1. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · 1 drug in this class
  2. St. Anne's University Hospital Brno, Czech Republic · 1 drug in this class
  3. Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan · 1 drug in this class
  4. University of Giessen · 1 drug in this class
  5. University of Miami · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tacrolimus/MMF — Competitive Intelligence Brief. https://druglandscape.com/ci/tacrolimus-mmf. Accessed 2026-05-15.

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